Results 51 to 60 of about 3,097,888 (408)

Effect of off-pump coronary surgery with right ventricular assist device on organ function and inflammatory response: a randomized controlled trial.

, 2002
BACKGROUND: Right ventricular assist devices (RVADs) have been proposed to improve exposure of the coronary arteries in off-pump surgery. In this study we investigated the impact of the A-Med RVAD on inflammatory response and organ function in patients ...
Angelini, Gianni D, Ascione, Raimondo, Caputo, Massimo, Marchetto, Giovanni, Narayan, Pradeep, Reeves, Barnaby C, Yeatman, Mark   +6 more
core   +1 more source

Health locus of control in patients undergoing coronary artery surgery – changes and associated outcomes: a seven-year cohort study [PDF]

, 2016
Introduction: Health locus of control is a measure of an individual’s beliefs in factors that are thought to determine health experiences. Scores are generated and form a graduated linear scale from external to internal control, with respect to their ...
Lindsay, Grace, Rideout, Andrew, Tolmie, Elizabeth   +2 more
core   +1 more source

Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality.

JAMA Surgery, 2016
IMPORTANCE Bariatric surgery is effective in reducing all-cause and cause-specific long-term mortality. Whether the long-term mortality benefit of surgery applies to all ages at which surgery is performed is not known.
L. Davidson, T. Adams, Jaewhan Kim, Jessica L. Jones, M. Hashibe, David Taylor, Tapan Mehta, R. McKinlay, S. Simper, Sherman C. Smith, S. Hunt   +10 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Isolated Human Pulmonary Artery Structure and Function Pre‐ and Post‐Cardiopulmonary Bypass Surgery

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundPulmonary dysfunction is a known complication after cardiac surgery using cardiopulmonary bypass, ranging from subclinical functional changes to prolonged postoperative ventilation, acute lung injury, and acute respiratory distress syndrome ...
Kim A. Dora, Christopher P. Stanley, Emad Al Jaaly, Francesca Fiorentino, Raimondo Ascione, Barnaby C. Reeves, Gianni D. Angelini   +6 more
doaj   +1 more source

Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response [PDF]

, 2002
Objective: Cyclooxygenase (COX)-2 is a key regulatory enzyme in the synthesis of prostanoids associated with trauma and inflammation. We investigated the COX-2 gene for functional variants that may influence susceptibility to disease.
Brull, D.J., Hill, M.R., Humphries, S.E., Laurent, G.J., Marshall, R.P., McAnulty, R.J., Papafili, A.   +6 more
core   +1 more source

Coronary bypass surgery

Medicine, 2002
Abstract Coronary artery bypass grafting (CABG) is entering a new era as minimally invasive techniques, off-pump surgery and total arterial revascularization have found roles in the surgical treatment of patients with coronary artery disease. The continued development of the techniques of percutaneous coronary intervention (PCI) is also having an ...
openaire   +2 more sources

Stroke in Coronary Bypass Surgery [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1982
ABSTRACT:A retrospective review of 253 patients who underwent coronary bypass surgery was performed. Eight (3.2%) had suffered a stroke either intra-operatively (4) or during the early post-operative period (4). A comparison of pre-operative and intra-operative variables between the stroke group and the stroke-free group showed a significant difference
Stanley A. Hashimoto, W.R. Wayne Martin
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source