Results 51 to 60 of about 72,809 (244)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

NGHIÊN CỨU HIỆU QUẢ KỸ THUẬT NUÔI SINH KHỐI TẢO CHLORELLA SP. SỬ DỤNG NƯỚC THẢI TỪ AO NUÔI CÁ TRA

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2013
Nghiên cứu về "Hiệu quả kỹ thuật nuôi sinh khối tảo Chlorella sp. sử dụng nước thải từ ao nuôi cá tra" được thực hiện trong 10 ngày. Thí nghiệm được bố trí hoàn toàn ngẫu nhiên với bốn nghiệm thức và ba lần lặp lại là nước cất (đối chứng), dung dịch ...
Trần Chấn Bắc
doaj  

CITY VIEWS [PDF]

open access: yes, 2012
[EN] The city as the architectural setting where life takes place has frequently been a subject for painters and draughtsmen. While it has also been addressed by other media - such as film, video and photography - which, with technology, have ...
Bigas, Montserrat   +2 more
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Gây nuôi thức ăn tự nhiên trong ao ương cá tra (Pangasianodon hypophthalmus)

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2018
Nghiên cứu được thực hiện trên sản phẩm bột dinh dưỡng thương mại (Supa-stock®) nhằm kích thích sự phát triển nguồn thức ăn tự nhiên là tảo và động vật phù du (ĐVPD) trong ao ương làm tăng khả năng bắt mồi và tăng trưởng của cá tra bột.
Âu Văn Hóa, Vũ Ngọc Út
doaj   +1 more source

16-19世紀中国Junkによるベトナム・フエとの海上貿易 [PDF]

open access: yes, 2010
VĂN HÓA - LỊCH SỬ HUẾ QUA GÓC NHÌN LÀNG XÃ PHỤ CẬN VÀ QUAN HỆ VỚI BÊN NGOÀI Session 3: Văn hoá - lịch sử Huế trong mối quan hệ với bên ngoài フエの文化と歴史:周辺集落と外部との関係からの視点より Session 3: Culture - history of Hue in relationship with the outside regions ...
Matsuura Akira, 松浦 章
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Valoración de la condición física para la salud [PDF]

open access: yes, 2003
Los componentes de la condición física para la salud tradicionalmente se han relacionado con el desarrollo de la resistencia cardiorrespiratoria, la fuerza y resistencia muscular, la elasticidad y la composición corporal.
Herrador Sánchez, Julio Ángel   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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