Results 221 to 230 of about 7,595,633 (393)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Cáncer de cérvix; respuesta a la Radioterapia y Quimioterapia concomitante en pacientes atendidos en el Centro Nacional de Radioterapia, 2010-2011 [PDF]

open access: yes, 2016
En Nicaragua, el cáncer de cérvix es una de las primeras causas de mortalidad por cáncer en el sexo femenino, en el 2012 se registró 934 casos a nivel nacional, y causó la muerte a 424 mujeres nicaragüenses Las tasas de supervivencia al cáncer cérvix son
Velásquez Silva, Anielka Lucía
core  

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Epidemiología del Cáncer del Cérvix en el Perú.

open access: hybrid, 1972
Mariano Bedoya H.   +2 more
openalex   +2 more sources

Factores de riesgo reproductivo asociados al cáncer mamario, en mujeres colombianas [PDF]

open access: gold, 1999
Patricia Olaya‐Contreras   +4 more
openalex   +1 more source

ADHERENCIA A PROGRAMAS DE DETECCIÓN SISTEMÁTICA DE CÁNCER EN PACIENTES ADULTOS MAYORES Y PRINCIPALES BARRERAS: UN ESTUDIO DE CORTE TRANSVERSAL

open access: yesREVISTA ARGENTINA DE MEDICINA
Introducción. La detección temprana de determinados tipos de cáncer se asocia a mejores resultados clínicos y disminución de la mortalidad; sin embargo, la adherencia a los programas vigentes no suele ser óptima. Nos proponemos evaluar el grado de conocimiento sobre la detección temprana de cáncer y la adherencia a los distintos programas vigentes en ...
openaire   +1 more source

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