Results 271 to 280 of about 393,854 (363)

Amazonian Cyanobacteria as a Source of Bioactive Compounds With Antimicrobial and Cytotoxic Properties

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Cyanobacteria are photosynthetic microorganisms known for producing diverse bioactive compounds. This study explores the bioactivity of extracts and fractions from Amazonian cyanobacteria and their pigment and phenolic compound production. A fraction from Synechococcus sp. CACIAM 05 showed cytotoxicity against hCMEC/D3 and MG‐63 cells.
Samuel Cavalcante do Amaral   +8 more
wiley   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains

open access: yesCytoskeleton, EarlyView.
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell   +4 more
wiley   +1 more source

Breast cancer in northern Peru: molecular subtypes and HER2 low. [PDF]

open access: yesRev Peru Med Exp Salud Publica
Gómez-Rázuri K   +3 more
europepmc   +1 more source

Intervención psicológica para manejo de ansiedad ante la colocación de catéter puerto en mujeres con cáncer de mama

open access: diamond, 2013
Isaías Vicente Lugo-González   +2 more
openalex   +2 more sources

Hsp90β‐Selective Inhibitors: Probing the Solvent‐Accessible Frontier

open access: yesChemMedChem, EarlyView.
The piperidinol ring of the KUNB106 scaffold (boxed in red) occupies the solvent‐exposed region of the Hsp90β ATP‐binding pocket, which provides a unique opportunity to optimize this region of the molecule. In the study disclosed herein, modifications such as CC bonds, heteroatoms, and three‐dimensionality result in improved inhibitors that further ...
Terin D’Amico   +8 more
wiley   +1 more source

Parámetros de la 18F-FDG PET/CT asociado con los factores pronósticos en la estadificación inicial del Cáncer de Mama

open access: diamond, 2019
Elfa Haro Salvatierra   +5 more
openalex   +2 more sources

Fluorescent Dyes for Probing Intracellular and Subcellular Polarity

open access: yesChemistry–Methods, EarlyView.
Fluorescent probes are crucial tools for measuring cellular microenvironment polarity, a parameter that influences physiological organelle function and diseases such as cancer. This text details the probes' physicochemical principles, intracellular targeting strategies, and key photophysical parameters for polarity estimation.
M. Carmen Gonzalez‐Garcia   +4 more
wiley   +1 more source

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