Results 291 to 300 of about 393,854 (363)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Content validity of guidance on self-care in the post-operative period for breast cancer. [PDF]

Rev Bras Enferm
Santos CPRSD, Goyanna NF, Corpes EF, Yanez RJV, Mourão Netto JJ, Barbosa RCM, Fernandes AFC.   +6 more
europepmc   +1 more source

Síntesis y actividad citotóxica de conjugados de la uridina con triterpenos en células de cáncer de mama

, 2016
Jhon Fernando Berrı́o Escobar, Manuel Pastrana Restrepo, Diana Marcela Mejía Cuartas, Diana Margarita Márquez Fernández, María Elena Márquez Fernández, Alejandro Martínez Martínez   +5 more
openalex   +2 more sources

Personalized Cancer Immunotherapy Boosted by cGAS‐STING‐Targeted Nanovaccines in Combination With Nutrient Modulation

Exploration, EarlyView.
The engineered bacteria (2'3'‐cGAMP@E.coli) is designed to synthesize intracellular 2'3'‐cGAMP, enabling the assembly of personalized nanovaccines (nECTs) through a bioconjugation with autologous tumor antigens, circumventing elaborate chemical production processes. The therapeutic impact of nECTs is significantly amplified when combined with a fasting‐
Wenping Huang, Guoliang Cao, Mixiao Tan, Fuhao Jia, Jie Zhang, Wen Su, Yue Yin, Hai Wang   +7 more
wiley   +1 more source

[Neuroendocrine expression markers in triple-negative, luminal-A, luminal-B and HER2neu breast cancer]. [PDF]

Rev Med Inst Mex Seguro Soc
Barboza-García YG, Ramírez-Balderrama L, Murguía-Pérez M, Hernández-González MA, Landeros-Navarro IY.   +4 more
europepmc   +1 more source

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, EarlyView.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Assessment of mental well-being and psychological distress in Moroccan breast cancer patients. [PDF]

Dement Neuropsychol
Haddou MB, El Mouaddib H, Haddou ZB, Khouchani M, Khoudri NE.   +4 more
europepmc   +1 more source

MORBILIDAD DEL CÁNCER DE MAMA EN LA MUJER [PDF]

, 1999
Raúl Morales González, Annarela Pollán Pérez   +1 more
openalex