Factores relacionados con la no participación en el programa de detección precoz de cáncer de mama
Pilar Barroso García+4 more
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Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel+17 more
wiley +1 more source
Dias MBK, Assis M, Santos ROM, Ribeiro CM, Migowski A, Tomazelli JG. Adequação da oferta de procedimentos para a detecção precoce do câncer de mama no Sistema Único de Saúde: um estudo transversal, Brasil e regiões, 2019. Cad Saúde Pública 2024; 40(5):e00139723. [PDF]
europepmc +1 more source
Efectividad Diagnóstica de la PET-FDG en el Cáncer de Mama. Revisión Sistemática y Meta-Análsis
Cristina Asensio-Del-Barrio+3 more
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Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty+8 more
wiley +1 more source
Abstract Introduction Testosterone therapy has become a cornerstone treatment for men with hypogonadism, offering significant benefits such as improved sexual function, mood, muscle mass, and bone density. However, concerns about its cardiovascular safety have historically tempered its use.
Michael Zitzmann+15 more
wiley +1 more source
Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley +1 more source
Factors associated with delayed initiation of breast cancer treatment at an oncology referral center in Juiz de Fora, Minas Gerais state, from 2010 to 2019: a cohort study. [PDF]
Silva FPCD, Souza MC, Bertoni N.
europepmc +1 more source
G protein‐coupled receptor‐mediated autophagy in health and disease
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan+2 more
wiley +1 more source