Results 51 to 60 of about 16,806 (224)
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang +9 more
wiley +1 more source
Latin America's cultural diversity, political instability, and socioeconomic inequality contribute to fragmented health systems, hindering high-quality care and health equity.
Pablo Mandó +6 more
doaj +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike +3 more
wiley +1 more source
Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women
This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani +4 more
wiley +1 more source
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
Autoexamen de mama: previene, actúa y consulta frente al cáncer de mama [PDF]
El cáncer de mama es una enfermedad cuya principal característica es la multiplicación de células malignas que se encuentran en la glándula mamaria. Esta patología presenta alteraciones sin control que pueden formar tumores que, al no ser tratados a ...
Bastidas Pantoja, Janneth Carina +5 more
core +2 more sources
Programa de Prevención de Cáncer de Mama, Instituto Nacional del Cáncer, Buenos Aires [PDF]
El Instituto Nacional del Cáncer ha realizado un Censo de Recursos Humanos y Moleculares en Cáncer Hereditario. OBJETIVOS: Identificar y categorizar consultorios de asesoramiento genético oncológico y laboratorios que realizan estudios moleculares en ...
Lina , Núñez +3 more
doaj
Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
wiley +1 more source

