Results 81 to 90 of about 183,594 (330)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

New neighbours: IV. 30 DENIS late-M dwarfs between 15 and 30 parsecs [PDF]

open access: yes, 2001
We present 30 new nearby (d<30 pc) red dwarf candidates, with estimated spectral types M6 to M8. 26 were directly selected from the DENIS database, and another 4 were first extracted from the LHS catalogue and cross-identified with a DENIS counterpart. Their proper motions were measured on the MAMA measuring machine from plates spanning 13 to 48 years,
arxiv   +1 more source

La mamografía como método de prevención secundaria en el cáncer de mama. Una revisión bibliográfica [PDF]

open access: yes, 2017
El cáncer de mama supone un problema grave de salud debido a su gran incidencia cada año en las mujeres. Tanto es así que constituye la primera causa de muerte por tumores malignos en mujeres.
Rodríguez Merino, Raquel
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Factores de riesgo y grado de conocimiento del cáncer de mama en pacientes, consulta externa del servicio de cirugía, Hospital Escuela César Amador Molina, enero a mayo 2014 [PDF]

open access: yes, 2015
En Nicaragua, de acuerdo con los datos del Centro Nacional de Radioterapia (CNR), el cáncer de mama es la segunda causa de morbilidad atendida con un 16.68%.
Blandón Arceda, Katherine Luxora   +1 more
core  

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Proper Motions of Pre-Main Sequence Stars in Southern Star-Forming Regions [PDF]

open access: yesarXiv, 2000
We present proper motion measurements of pre-main sequence (PMS) stars associated with major star-forming regions of the southern hemisphere (Chamaeleon, Lupus, Upper Scorpius - Ophiuchus, Corona Australis), situated in the galactic longitude range l = 290\degr to l = 360\degr.
arxiv  

Cáncer de mama y ¿Políticas de prevención? [PDF]

open access: yes, 2014
Para cumplir con el objetivo del ensayo es necesario responder dos preguntas esenciales: 1) ¿qué papel ha jugado la Norma para la prevención, diagnóstico, tratamiento, control y vigilancia epidemiológica del cáncer de mama en las últimas dos décadas en ...
Nieto Manzano, Lina Alejandra   +1 more
core  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Educação em saúde para detecção precoce do câncer mamário em mulheres cegas

open access: yesRev Rene, 2015
Objetivo: evaluar el conocimiento de mujeres ciegas sobre los factores de riesgo para el cáncer de mama y se ellas buscan la detección precoz de este cáncer.
Inacia Sátiro Xavier de França   +5 more
doaj  

Home - About - Disclaimer - Privacy