Results 41 to 50 of about 58,974,300 (144)

Computation of Protein Thermostability and Epistasis

WIREs Computational Molecular Science, Volume 15, Issue 5, September/October 2025.
Conceptual illustration of computational prediction of protein thermostability and mutational epistasis. A neural network algorithm models changes in heat‐induced (un)folding by correlating sequence mutations with variations in free energy. The nonadditive nature of epistatic mutations is metaphorically represented by Orwell's infamous quote from ...
Francesca Peccati, Cristina M. Segovia, Reyes Núñez‐Franco, Gonzalo Jiménez‐Osés   +3 more
wiley   +1 more source

Endoscopic ultrasound‐guided tissue acquisition for focal liver lesions in patients with a history of multiple primary malignant neoplasms

DEN Open, Volume 5, Issue 1, April 2025.
Abstract Objective This study aimed to investigate the usefulness of endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) for diagnosing focal liver lesions in patients with a history of multiple primary malignant neoplasms. Methods Among patients who underwent EUS‐TA for focal liver lesions between 2016 and 2022, those with a history of multiple ...
Yuichi Takano, Naoki Tamai, Masataka Yamawaki, Jun Noda, Tetsushi Azami, Fumitaka Niiya, Fumiya Nishimoto, Naotaka Maruoka, Tatsuya Yamagami, Masatsugu Nagahama   +9 more
wiley   +1 more source

Actualización sobre cáncer de próstata

Correo Científico Médico, 2017
El cáncer de próstata es una neoplasia hormono-dependiente de importante heterogeneidad. El comportamiento clínico, la respuesta a tratamientos y la supervivencia varían dependiendo de cada paciente.
Ana Isabel Ruiz López, Juan Carlos Pérez Mesa, Yanelis Cruz Batista, Lienny Eliza González Lorenzo   +3 more
doaj   +2 more sources

Chaperon‐Abgeleitete Kupfer(I)‐Bindende Peptidnanofibrillen stören die Kupferhomöostase in Krebszellen

Angewandte Chemie, Volume 136, Issue 51, December 16, 2024.
Wir präsentieren ein von Chaperonen abgeleitetes Cu+‐bindendes Peptid, das das konservierte MTCGGC−Cu+‐Bindungsmotiv enthält und sich innerhalb von Krebszellen zu Nanofibrillen selbstassembliert. Diese Nanofibrillen besitzen mehrere MTCGGC−Cu+‐Bindungsmotive auf ihrer Oberfläche, wodurch eine effiziente Bindung intrazellulärer Cu+‐Ionen ermöglicht wird.
M. T. Jeena, Julian Link, Jian Zhang, Iain Harley, Petri Turunen, Robert Graf, Manfred Wagner, Luis Andre Baptista, Hendrik R. A. Jonker, Liyang Cui, Ingo Lieberwirth, Katharina Landfester, Jianghong Rao, David Y. W. Ng, Tanja Weil   +14 more
wiley   +1 more source

Factores que influyen en la gestión del cáncer de próstata [PDF]

, 2020
[ES]Objetivos de la tesis: 1.-Conocer las características principales de los de pacientes con cáncer de próstata órgano-confinado según la opción de tratamiento indicada.
Alonso Prieto, Miguel Ángel, Miguel Ángel Alonso Prieto   +1 more
core   +1 more source

Programa de prevención primaria en cáncer de próstata [PDF]

, 2003
Según los datos epidemiológicos de la población colombiana, ofrecidas por el Instituto Nacional de Cancerología (INC), el cáncer de próstata ocupó el séptimo lugar dentro de los tipos de cáncer más frecuentes en el país en el año 2000, esta afección ...
Figueroa Puello, Jessica, Joly Dueñas, Rafael, Ramírez Molina, Marcela, De La Rosa, Jaime   +3 more
core   +1 more source

Die Herausforderungen der molekularen Interpretationen von Infrarotspektren komplexer Proben

Angewandte Chemie, Volume 136, Issue 50, December 9, 2024.
Die Schwingungsspektroskopie ist ein leistungsstarkes Werkzeug zur molekularen Fingerabdruckanalyse. Dennoch ist die Interpretation von IR‐Spektren molekular komplexer Medien herausfordernd. In dieser Arbeit beleuchten wir die oft übersehenen Feinheiten der spektralen Datenanalyse und diskutieren häufig gemachte Fehlinterpretationen der Daten. Im Fokus
Tarek Eissa, Liudmila Voronina, Marinus Huber, Frank Fleischmann, Mihaela Žigman   +4 more
wiley   +1 more source

ASSISTÊNCIA DE ENFERMAGEM AO HOMEM COM CÂNCER DE PRÓSTATA: REVISÃO INTEGRATIVA DA LITERATURA

Revista Uningá, 2017
O câncer de próstata é o segundo em incidência das neoplasias que acometem o homem, portanto, requer do profissional da saúde, especialmente o enfermeiro, atenção especial para o aconselhamento de medidas preventivas e curativas, objetivando a promoção ...
CLAUDIA MARIA SOUSA DE CARVALHO, RAFAELLA PLÁCIDO AMORIM CARDOSO, IRLANDIA CONRADO RIBEIRO, CRISTIANE GOMES SIQUEIRA CRAVEIRO, FERNANDA CLÁUDIA MIRANDA AMORIM, CAMILA APARECIDA PINHEIRO LANDIM ALMEIDA   +5 more
doaj  

European validation of the Barcelona magnetic resonance predictive model for significant prostate cancer detection in prostate biopsies

BJUI Compass, Volume 7, Issue 4, April 2026.
Juan Morote, Berta Miró, Lucas Regis, François Cousin, Patrick Duflot, Philippe Kolh, Alice Andalò, Nicola Gentili, Filippo Merloni, Andrea Prochowski Iamurri, Fabio Ferroni, Enrique Trilla, Olga Méndez   +12 more
wiley   +1 more source

Does Fusobacterium in Colorectal Cancer Sites Originate From the Oral Cavity? A Pilot Study

Clinical and Experimental Dental Research, Volume 10, Issue 6, December 2024.
ABSTRACT Objectives Fusobacterium can contribute to oral diseases, but also pose as a systemic risk factor. This genus, and especially F. nucleatum, can be found in colorectal cancer (CRC) tissue and is involved in multiple aspects of this type of cancer. Previous studies indicated a possible oral origin of these bacteria; however, stronger evidence is
Niels Plomp, Kristina Bertl, Marie‐Louise Lydrup, Klas Sjöberg, Hermie J. M. Harmsen, Andreas Stavropoulos   +5 more
wiley   +1 more source