Results 11 to 20 of about 117,116 (162)

Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis

open access: yesCancer Cell International, 2021
Background Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene (e.g. PTEN) or microRNAs (e.g. miR-
Yue Chang   +5 more
doaj   +1 more source

PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway

open access: yesCell Death and Disease, 2023
PDIA6 have been reported to be involved in a variety of cancers, however, the underlying role in endometrial cancer is still unclear. In this study, we aimed to study the function of PDIA6 in endometrial cancer.
Pengling Wang   +6 more
doaj   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

open access: yesScientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah   +8 more
doaj   +1 more source

Endometrial cancer with concomitant endometriosis is highly associated with ovarian endometrioid carcinoma: a retrospective cohort study

open access: yesBMC Women's Health, 2022
Background Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes in the uterine
Aya Ishizaka   +13 more
doaj   +1 more source

Relationship between duration of breast feeding and endometrial cancer: a case-control study [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The incidence of endometrial cancer is increasing in Iran. The risk of endometrial cancer is related to estrogen levels that breastfeeding reduces it. This
Zohreh Yeganeh   +5 more
doaj   +1 more source

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT

open access: yesAnimal Cells and Systems, 2021
Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered transmembrane protein, which may be related to the invasion, metastasis of the tumor and the ...
Huan Xiao   +4 more
doaj   +1 more source

Accuracy of Pre-operative Endometrial Sampling for the Detection of High Grade Endometrial Cancer

open access: yesThai Journal of Obstetrics and Gynaecology, 2015
Objective:To assess the accuracy of endometrial sampling for detection of high grade endometrial cancer.Materials and Methods: This study was a diagnostic test.
Uraiwan Khomphaiboonkij   +1 more
doaj   +1 more source

Prognostic value of angiogenic markers of endometrial cancer (literature review)

open access: yesСибирский онкологический журнал, 2022
Endometrial cancer is the most common cancer of the female reproductive organs. The purpose of the study was to summarize the available data on the role of angiogenic markers in the development, progression and prognosis of endometrial cancer.
N. S. Zolotukhina, L. F. Gulyaeva
doaj   +1 more source

Risk Factors for Endometrial Lesions Detected by Hysteroscopy in Breast Cancer Patients Taking Tamoxifen [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Breast cancer has become the most common malignant tumor threatening the health of Chinese women in recent years. The use of tamoxifen (TAM) has successfully reduced the recurrence and progression of estrogen receptor-positive breast cancer ...
LI Yujing, JIN Yichao, CHEN Xing, JI Mengying, DAI Huihua
doaj   +1 more source

Does Preoperative Diagnosis of Endometrial Hyperplasia Necessitate Intraoperative Frozen Section Consultation?

open access: yesBalkan Medical Journal, 2016
Background: In women with endometrial hyperplasia, there is a risk for co-existent endometrial cancer when patients are subjected to immediate surgical treatment.
Gokhan Boyraz   +4 more
doaj   +1 more source

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