Results 181 to 190 of about 605,346 (215)

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He   +9 more
wiley   +1 more source

A Randomized Controlled Phase 3 Trial of Oral Prednisolone Administration Versus Local Triamcinolone Injection Therapy for Esophageal Stricture Prevention After Extensive Endoscopic Submucosal Dissection (JCOG1217). [PDF]

open access: yesDig Endosc
Tanaka M   +14 more
europepmc   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu   +10 more
wiley   +1 more source

Comprehensive benchmarking of deep learning architectures for multiclass histopathological classification of oral epithelial lesions. [PDF]

open access: yesJ Oral Biol Craniofac Res
Bharti A   +7 more
europepmc   +1 more source

Correction to: Systematic review of prophylactic antibacterial agents for radiation‑induced oral mucositis in head and neck cancer. [PDF]

open access: yesSupport Care Cancer
Alicea DS   +8 more
europepmc   +1 more source

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