Results 51 to 60 of about 605,346 (215)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Pérdida de la expresión antigénica ABH en pacientes con lesiones orales precancerosas y cancerosas Loss of ABH antigenic expression in patients with precancerous and cancerous oral lesions

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2008
Los antígenos ABH, productos de la interacción de 2 sistemas genéticos, Hh y ABO, están sujetos a leyes de herencia y pueden estar localizados no sólo en los eritrocitos, sino también en la mayoría de las células humanas. El objetivo del este trabajo fue
Carlos Campi   +6 more
doaj  

Clinical outcomes of oral cancer patients who survive for more than 5 years in Taiwan

open access: yesJournal of the Formosan Medical Association, 2019
Background/Purpose: Oral cancer patients who survive for more than 5 years are supposed to have a reduced local cancer recurrence rate and survive longer.
Hou-Chiang Chou   +6 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Photodynamic Therapy, a new approach in the treatment of oral cancer Terapia Fotodinámica, un nuevo acercamiento en el tratamiento del cáncer oral

open access: yesSalud UIS, 2010
The worldwide incidence of head and neck cancer is, approximately, 640,000 new cases per year. Oral cancer accounts for one third of all cancers and it is the eighth most diagnosed in men.
Leandro Santos Bicalho   +4 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Linfoma primario difuso de células B grandes de mucosa gingival, en paciente VIH y EBV negativos

open access: yesRevista del Hospital Italiano de Buenos Aires
El linfoma difuso de células B grandes (LDCBG) es el linfoma más frecuente. La presentación clínica puede ser nodal o extranodal y sus síntomas dependen de la localización tumoral; en la mayoría de los casos están asociados a algún tipo de ...
Tomás Richards
doaj  

Análisis de salud oral en Uruguay. OMS vs otras fuentes

open access: yesOdontoestomatología
La prevalencia mundial combinada de caries dental, enfermedad periodontal y pérdida de dientes se ha  mantenido sin cambios y es la más alta que cualquier otra enfermedad no transmisible.
Enrique Rotemberg   +6 more
doaj   +1 more source

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