Results 121 to 130 of about 3,759,081 (281)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

COMPORTAMIENTO DE LA FAMILIA FRENTE AL DIAGNÓSTICO DE CÁNCER DE MAMA.

Enfermería Global, 2007
El cáncer de mama acostumbra a generar sentimientos de miedo, tristeza y negación en la mujer y en los familiares. El objetivo fue analizar el comportamiento de la familia frente al diagnóstico de cáncer de mama.
E. Mesquita Melo, R. Magalhães da Silva, A.M. De Almeida, A. F. Carvalho Fernández, C. D. Mota Rego   +4 more
doaj   +1 more source

Dinámica familiar: percepción de familias de sobrevivientes de cancer de mama [PDF]

, 2009
O estudo teve como objetivo identificar as percepções de familiares sobre a dinâmica de suas famílias após o câncer de mama em um dos seus membros. Estudo de abordagem qualitativa que tomou como referencial teórico o modelo de funcionamento familiar ...
BIFFI, Raquel Gabrielli, MAMEDE, Marli Vilela   +1 more
core   +3 more sources

Metodología de cáncer de mama para la maximización de recursos utilizada actualmente en México

Gaceta Mexicana de Oncología
Antecedentes: El cáncer de mama es la principal causa mundial de muerte por neoplasias. Por lo tanto, los centros médicos deben estar preparados para evaluar la gestión óptima de sus recursos, buscando el mejor resultado clínico. Objetivo: Presentar un modelo aplicado para la cuantificación y toma de decisiones informadas por parte de un servicio de ...
Juan E. Bargalló, José J. Ramírez, Javier Picó-Guzmán, José Ma. Abellán-Perpiñán   +3 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Avaliação da atividade genotóxica do composto cloreto de cis-tetr aaminodiclororutênio (iii) sobre cultura de linfócitos do sangue periférico

Revista de Biologia Neotropical, 2010
Vários compostos metálicos, reconhecidos como potentes agentes antitumorais, têm sido desenvolvidos e testados in vivo e in vitro. Entre os primeiros complexos metálicos empregados no tratamento de tumores sólidos pode-se citar a cisplatina.
Alessandra de Santana Braga Barbosa Ribeiro
doaj  

Autocuidado e apoio social em mulheres do Núcleo Mama Porto Alegre [PDF]

, 2014
Breast cancer is one the most prevalent types of cancer among women. Many causes are known, ranging from the biological to the psychosocial. In Rio Grande do Sul, especially in Porto Alegre, occurrence rates and fatalities due to breast cancer are some ...
Hermel, Júlia Schneider
core