Results 151 to 160 of about 3,892,843 (246)

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review. [PDF]

Scand J Caring Sci
Puusa N, Harju E, Kalliomäki ML, Haavisto E.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Nonlinear Aging of the Human TCR Repertoire Is Influenced by Sex, CMV, and Cancer. [PDF]

Aging Cell
Lange N, Attermann AK, Juul RI, Andersen L, Nordentoft I, Jessen LE, McGranahan N, Aerts HJWL, Dyrskjøt L, Birkbak NJ.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hemophagocytic syndrome associated with cytomegalovirus infection in a severely immunocompromised AIDS patient: case report

Brazilian Journal of Infectious Diseases
Marcus V.F. Nogueira, Laira Vidal, Bruno Terra, Thiago Pagot, Jorge I.F. Salluh, Márcio Soares   +5 more
doaj   +1 more source

Japanese Society for Hereditary Tumors Guidance: Hereditary Cancer Syndromes With Multigene Panel Testing, 2025 Edition. [PDF]

Cancer Sci
Yoshida R, Hirasawa A, Imoto I, Yamaguchi T, Kumamoto K, Momoko A, Ueki A, Masuda K, Urakawa Y, Tanabe N, Watanabe A, Hirata M, Aruga T, Kuwata T, Okugawa Y, Kaneko K, Terui-Kohbata H, Matsumoto M, Ueno S, Oda K, Ono H, Sakurai A, Matsui H, Yamamoto G, Yamamoto H, Yamamoto Y, Ikegami M, Ohkuma Y, Shien K, Suzuki S, Takayanagi S, Tanabe M, Hasumi H, Hatta N, Hattori H, Matsubayashi H, Yamagami W, Yamada M, Oishi K, Oka T, Oda S, Kobayashi Y, Takekoshi K, Nakajima T, Nakano Y, Nakayama Y, Miura F, Miyakura Y, Mori Y, Yoshimura A, Yonamine M, Shigeyasu K, Fujita H, Futagawa M, Ohta K, Kawano J, Tokutomi T, Sato A, Makabe T, Yoshihama T, Aitani M, Kimura K, Takaiso N, Tomozawa C, Hiraoka Y, Matsukawa M, Ishida H.   +66 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Administrative Workload and Associated Distress in Individuals Undergoing Cancer Therapy. [PDF]

Cancer Med
Boyle SJ, Parsons HM, Kyle MA, Jewett P, Yang G, Huang Z, Gupta A, Teoh D, Fan Y, Blaes A, Arend R, Rocque GB, Wolfson J, Vogel RI.   +13 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Updated cancer risks in lynch syndrome. [PDF]

Fam Cancer
Drogan CM, Kupfer SS.
europepmc   +1 more source