Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Correction: Integrated multi-omics analysis reveals clinical significance of hepatocyte nuclear factor-1β in tumor immune microenvironment, immunotherapy and prognostic prediction for colon adenocarcinoma. [PDF]
Gao F +7 more
europepmc +1 more source
Prevalência e características da dor neuropática e neuropatia periférica em doentes submetidos à oxaliplatina para tratamento do câncer colorretal [PDF]
Nathália Scisci
openalex +1 more source
Assistência de enfermagem ao câncer renal: um relato de experiência
Kelly Teixeira Santos +2 more
openalex +2 more sources
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis. [PDF]
DuBois TD +4 more
europepmc +1 more source
Breast cancer: a future challenge for health systems in developing countries [PDF]
TIEZZI, Daniel Guimarães
core +2 more sources
Indicadores Bibliométricos Dos Artigos Sobre “Caquexia E Câncer” na Base Scopus
Clarissa de Oliveira Soares Peixoto +10 more
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source

