Results 221 to 230 of about 8,254,551 (385)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Análise descritiva da mortalidade por câncer de pulmão no município de São Paulo de 2005 a 2014

open access: diamond, 2018
Igor Bastos Polônio   +3 more
openalex   +1 more source

IMPACTO DAS NOVAS TERAPIAS NO MANEJO DO CÂNCER DE PRÓSTATA [PDF]

open access: gold, 2023
Cristiano Borges Lopes   +9 more
openalex   +1 more source

Câncer na infância no Rio de Janeiro: distribuição epidemiológica e características da atenção a saúde [PDF]

open access: yes, 2004
Este estudo foi contratado junto à Escola Nacional de Saúde Pública da FIOCRUZ, tendo em vista oferecer um retrato da realidade epidemiológica e dos serviços ofertados para o tratamento do câncer infantil no Estado do Rio de Janeiro e gerar subsídios ao ...
Sergio Koifman
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Dermatologist-level classification of skin cancer with deep neural networks

open access: yesNature, 2017
A. Esteva   +6 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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