Results 311 to 320 of about 8,254,551 (385)
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
Cancer Discovery, 2012 E. Cerami, Jianjiong Gao, U. Dogrusoz, Benjamin E. Gross, S. O. Sumer, B. A. Aksoy, A. Jacobsen, Caitlin J. Byrne, M. Heuer, E. Larsson, Yevgeniy Antipin, B. Reva, A. P. Goldberg, C. Sander, N. Schultz +14 moresemanticscholar +1 more sourcePerspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman +13 morewiley +1 more sourceNext-generation characterization of the Cancer Cell Line Encyclopedia
Nature, 2019 M. Ghandi, F. Huang, Judit Jané-Valbuena, G. Kryukov, Christopher C. Lo, E. McDonald, J. Barretina, Ellen T. Gelfand, C. Bielski, Haoxin Li, K. Hu, Alexander Y. Andreev-Drakhlin, Jaegil Kim, J. Hess, B. Haas, F. Aguet, B. Weir, M. Rothberg, B. Paolella, M. Lawrence, Rehan Akbani, Yiling Lu, Hong L. Tiv, P. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, J. Shih, Kevin Hadi, Yanay Rosen, J. Bistline, K. Venkatesan, Anupama Reddy, D. Sonkin, Manway Liu, J. Lehár, Joshua M. Korn, D. Porter, Michael D. Jones, J. Golji, G. Caponigro, Jordan E. Taylor, C. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, A. Kauffmann, Nicolas Stransky, M. Imieliński, Y. Maruvka, A. Cherniack, Aviad Tsherniak, F. Vazquez, Jacob D. Jaffe, A. Lane, D. Weinstock, Cory M. Johannessen, Michael P. Morrissey, F. Stegmeier, R. Schlegel, W. Hahn, G. Getz, G. Mills, J. Boehm, T. Golub, L. Garraway, W. Sellers +67 moresemanticscholar +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourceNext‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner +4 morewiley +1 more sourceBreast cancer risk level and prediction of tumor aggressiveness in the Athena Breast Health Network. [PDF]
Breast Cancer Res TreatLeggat-Barr K, Lewis T, Tice JA, Tsopurashvili E, Sayaman R, Warner P, Malvin K, Sabacan L, Perry-Solomon A, Theiner S, Acerbi I, Griffin A, McGuire J, Lee V, Borowsky AD, Wisdom Study and Athena Breast Health Network Investigators and Advocate Partners, Eklund M, Kaplan C, Hiatt RA, Fiscalini AS, Kerlikowske K, Shieh Y, Esserman L, Van't Veer L. +23 moreeuropepmc +1 more source
