Results 211 to 220 of about 407,179 (246)

Estudo sobre preferência de Alimentos compostos completos para cães [PDF]

, 2013
Mariana Fidalgo Ferro de Beça
core  

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Polymer-metal oxide interfaces in XHNBR/PA6 blends: computational insights toward sustainable crosslinking. [PDF]

RSC Adv
Calvo U, Matxain JM, Egurrola JJ, Burgoa A, Ruipérez F.   +4 more
europepmc   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

Reshaping Clinical Destiny of Silent ALCAPA: Multimodal Imaging-Driven Early Diagnosis and Mandatory Intervention. [PDF]

Clin Case Rep
Cheng Y, Li J, Chen H, Wang X, Ma X, Cao Y.   +5 more
europepmc   +1 more source

The Maize ZmbHLH118 Transcription Factor Regulates Vacuolar Nitrate Loading by the NO3− Transporter ZmCLCa

Advanced Science, EarlyView.
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang, Elsa Demes‐Causse, Xujian Li, Zhenhui Guo, Hanshu Zhao, Huairong Cao, Yajing Song, Lijun Mu, Kaikai Zhang, Jing Zhang, Zhongtao Jia, Lixing Yuan, Alexis De Angeli, Jingbo Zhang   +13 more
wiley   +1 more source

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway. [PDF]

Int J Mol Med
Guo LH, Cao Y, Zhuang RT, Han Y, Li J.
europepmc   +1 more source

Estimativa e caracterização da população de cães e gatos na Ilha do Maio, Cabo Verde: Integração entre dados de um recenseamento e imagens de detecção remota [PDF]

, 2014
Bryssinckx, W., Ducheyne, E., Lopes Antunes, Ana Carolina, Malta, M., Vieira, S.   +4 more
core  

Ferroelectric‐Polarization‐Driven Structural Engineering of Bi3Nb17O47 Anodes for High‐Performance Lithium‐Ion Batteries

Advanced Science, EarlyView.
A transformative ferroelectric‐polarization strategy is employed to overcome the intrinsic limitations of tungsten bronze (TTB)‐type anode materials in metal‐ion batteries, using Bi3Nb17O47 as a model system. By exploiting the non‐centrosymmetric crystal structure and field‐induced ionic displacements, controlled structural engineering with ...
Xiaoming Lou, Songjie Li, Chunfu Lin, Yanchao Li, Mingze Sun, Zhen Liu, Weiye Nie, Xiaolong Tang, Baoming Wang, Wenwu Cao, Renchao Che   +10 more
wiley   +1 more source

RSM-optimized biodiesel production from Ethiopian Podocarpus falcatus seed oil using a CaO-CeO₂ heterogeneous composite catalyst and oxidative stability assessment. [PDF]

Sci Rep
Birhanu B, Deshmukh D, Hailelule T, Yeneneh K.   +3 more
europepmc   +1 more source