Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li +12 more
wiley +1 more source
Correction: Mechanism of action of curculigoside ameliorating osteoporosis: an analysis based on network pharmacology and experimental validation. [PDF]
Wei C, Zhang W, Lou C, Li N, Cao H.
europepmc +1 more source
Tratamento cirúrgico de um caso de meningioma cortical frontal em cão – relato de caso
Jorge Piovesan Conti +6 more
openalex +1 more source
Sobre um caso de capilaríase hepática em cão
Adayr Mafuz Saliba +2 more
openalex +2 more sources
Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao +25 more
wiley +1 more source
Mechanical and Environmental Properties of Cemented Paste Backfill Prepared with Bayer Red Mud as an Alkali-Activator Substitute. [PDF]
Gao L, Zhao H, Guo N, Jiang X, Zhang Y.
europepmc +1 more source
Tumor de células de sertoli e seminoma difuso em cão com criptorquidismo bilateral - Relato de caso.
Fernanda Vieira Henrique +3 more
openalex +1 more source
Carcinoma de células renais sólido em cão
Lara Moreira Feitosa de Alencar Santos +3 more
openalex +1 more source
Características citológicas de cistoadenocarcinoma papilar ovariano em um cão
Tamires Ramborger Antunes +7 more
openalex +2 more sources
Context associated with morphine withdrawal elicits an increase in serum corticosterone levels. Corticosterone participates in CTR‐MWM by acting on MR, but not GR, in the BLA. MR in BLA→NAcC neurons mediates CTR‐MWM. MR increases presynaptic glutamate release and meanwhile participates in D1 receptor‐induced increases in presynaptic glutamate release ...
Zixuan Cao +15 more
wiley +1 more source

