A young patient with lower limb Ewing's sarcoma experienced a cerebral infarction: A care-compliant case report. [PDF]
Zhang SW, Cao DX.
europepmc +1 more source
Estimativa e caracterização da população de cães e gatos na Ilha do Maio, Cabo Verde: Integração entre dados de um recenseamento e imagens de detecção remota [PDF]
Bryssinckx, W. +4 more
core
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao +14 more
wiley +1 more source
The effectiveness and safety of Yi Guan Jian decoction in the treatment of primary liver cancer: A systematic review and meta-analysis of randomized controlled trials. [PDF]
He Z, Cao X, Zhao L, He S.
europepmc +1 more source
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei +10 more
wiley +1 more source
The forgotten airway: central airway pathology in the ICU. [PDF]
Marchioni A +9 more
europepmc +1 more source
Cinco Casos Clínicos de Medicina e Cirurgia de Animais de Companhia [PDF]
Mariana Matilde Antunes Vieira
core
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu +13 more
wiley +1 more source
Correction: CT radiomics‑based explainable machine learning model for accurate differentiation of malignant and benign endometrial tumors: a two‑center study. [PDF]
Zhang T +11 more
europepmc +1 more source
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li +12 more
wiley +1 more source

