Results 281 to 290 of about 1,024,204 (346)

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Artrite séptica em cão. Relato de caso

, 2003
Thomas Champion, Paula Sincero, Rosângela Locatelli Dittrich, Marie-Laure Franco, G. Sprea, D. L. K. Baudi, G. B. Silva   +6 more
openalex   +2 more sources

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Smoldering Treatment of PFAS: Investigation of Mass Balance and Volumetric Scale Up for Field Implementation. [PDF]

ACS Omega
Harrison BG, Major DW, Kinsman LL, Brown JK, Gabayet JLD, Gerhard JI, Patch DJ, Weber KP, Chernysheva L, Brown GM, Doudrick K, Abarca-Perez A, Peaslee GF, Pennell KD, Manz KE.   +14 more
europepmc   +1 more source

Rabdomiossarcoma de vesícula urinária em cão da Serra da Estrela adulto jovem. Relato de caso

, 2003
P. Horta, P. T. D. Silva, Carla Alice Berl, Maria Carolina Catai Chalita, Francisco Maia, L. M. Kanayama   +5 more
openalex   +2 more sources

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

MYC/TET3‐Regulated TMEM65 Activates OXPHOS‐SERPINB3 Pathway to Promote Progression and Cisplatin Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang, Min‐Ying Huang, Shao‐Ying Yang, Jia‐Yang Cai, Qian Zhao, Fang‐Lin Zhang, Xin Hu, Zhi‐Min Shao, Li Liao, A‐Yong Cao, Da‐Qiang Li   +10 more
wiley   +1 more source

Correction: Impaired sensitivity to thyroid hormones is associated with high lipoprotein(a) level in euthyroid patients with type 2 diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Zhong L, Lin R, Cao B, Zhong W, Tu M, Wei W.   +5 more
europepmc   +1 more source

Releasing 8.0 wt.% H2 from the LiBH4−2LiNH2 Composite within 5 Min under Light Illumination

Advanced Science, EarlyView.
The N−H bond in the [NH2]− ion group is significantly weakened by the non‐thermal effect of UV light, leading to a 60‐fold increase in dehydrogenation rate at the same temperature. As a result, over 8.0 wt.% H2 is released within 5 min. Abstract The absence of safe and efficient hydrogen storage technologies is the major bottleneck for widespread ...
Haoyang Yu, Zibo Cheng, Hong Wen, Han Wang, Qijun Pei, Yeqin Guan, Hujun Cao, Ping Chen   +7 more
wiley   +1 more source

Correction: Plumbagin protects mice from lethal Sepsis by modulating immunometabolism upstream of PKM2. [PDF]

Mol Med
Zhang Z, Deng W, Kang R, Xie M, Billiar T, Wang H, Cao L, Tang D.   +7 more
europepmc   +1 more source