Results 301 to 310 of about 1,024,204 (346)

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

open access: yesAdvanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang   +17 more
wiley   +1 more source

Correction: Decoy-PROTAC for specific degradation of "Undruggable" STAT3 transcription factor. [PDF]

open access: yesCell Death Dis
Li S   +10 more
europepmc   +1 more source

Venda por grosso de luxo Piscina confortável Cão Gato Bag Carrier Acessórios Pet

open access: gold, 2001
Marcela Abbado Neres   +5 more
openalex  

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen   +18 more
wiley   +1 more source

ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy

open access: yesAdvanced Science, EarlyView.
The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li   +11 more
wiley   +1 more source

A Case of Secondary Syphilis on Infant. [PDF]

open access: yesClin Cosmet Investig Dermatol
Cao Z, Wang ZH, Sun AJ.
europepmc   +1 more source

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