Results 31 to 40 of about 10,361,601 (162)

INOVAÇÕES E DESAFIOS NA TERAPIA COM CÉLULAS CAR-T: DA MODELAGEM EM LEUCEMIA CRÔNICA À SINERGIA COM CÉLULAS NK

Hematology, Transfusion and Cell Therapy
Introdução: A terapia CAR-T usa células T do próprio paciente modificadas geneticamente para combater o câncer. Estudos mostram que a CAR-T direcionada ao CD19 é eficaz contra leucemias, especialmente a leucemia linfoblástica aguda recidivante/refratária.
GS Correa, SZ Jorge, HC Silva, AC Ramalho, MBC Silveira, LFT Ribeiro, MEJ Marinho, RVP Souza, PHSCD Santos, G Suhett   +9 more
doaj   +1 more source

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

New Phytologist, Volume 251, Issue 3, Page 1578-1594, August 2026.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski   +4 more
wiley   +1 more source

Selantes vitrocerâmicos para células a combustível de óxido sólido [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2010As células a combustível (CaC) são uma das mais promissoras alternativas de geração de
Rachadel, Priscila Lemes
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Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, Volume 28, Issue 14, 22 July 2026.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Adenocarcinoma de células renais. [PDF]

, 1992
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Souza, Luiz Paulo de
core  

Fotoferese extracorpórea Extracorporeal photopheresis

Revista Brasileira de Hematologia e Hemoterapia, 2008
Fotoferese extracorpórea é uma modalidade de terapia celular que tem demonstrado eficácia e segurança em pacientes portadores de doenças auto-imunes e mediadas por células T, incluindo esclerodermia, linfoma de células T cutâneo/ Síndrome de Sézary e ...
Márcia M. Silva, Luis Fernando S. Bouzas   +1 more
doaj   +1 more source

Antigonococcal Activity and Cytotoxicity Screening of Three Ziziphus Species Indigenous to South Africa

Chemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Ziziphus species in South Africa are widely used to treat gonorrhea; however, to this day, there has been no scientific validation of their ethnomedicinal use. This study tentatively identified phytol, betulin, and hexadecanoic acid to be linked to the observed antigonococcal activity.
Mcebisi J. Mabuza, Marcel Kaiser, Thilivhali E. Tshikalange, Abdullahi A. Yusuf, Mahwahwatse J. Bapela   +4 more
wiley   +1 more source

Avaliação do potencial mielossupressor do mesilato de imatinibe sobre células progenitoras hematopoiéticas e células do estroma da medula óssea de camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-graduação em Farmácia, Florianópolis, 2009.Os agentes antineoplásicos atingem células que estão em processo de divisão celular, assim, a rápida ...
Soares, Pâmela de Brum
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Integrative Transcriptomic and Functional Analysis of PKMYT1 Reveals a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

Hematological Oncology, Volume 44, Issue 4, July 2026.
ABSTRACT Chronic lymphocytic leukemia (CLL) is a clinically and molecularly heterogeneous disease. PKMYT1, a G2/M cell cycle kinase, has been implicated in tumor progression in several cancers, but its role in CLL remains unclear. We evaluated PKMYT1 expression in primary CLL samples and analyzed associations with cytogenetic features and clinical ...
Elizabete Cristina Iseke Bispo, Cláudia de Souza Lima Pontes, Jennifer Martins do Nascimento, Fábio Wilson de Lima Alves, Juliana Lott de Carvalho, Antônio Roberto Lucena‐Araujo, Felipe Saldanha‐Araujo   +6 more
wiley   +1 more source

Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection

Anais da Academia Brasileira de Ciências, 2008
Following infection with Leishmania major, T cell activation and apoptosis can be detected in draining lymph nodes of C57BL/6-infected mice. We investigated the mechanisms involved in apoptosis and cytokine expression following Tcellactivation. After two
Wânia F. Pereira, Landi V.C. Guillermo, Flávia L. Ribeiro-Gomes, Marcela F. Lopes   +3 more
doaj   +1 more source