Uncovering Cas9 PAM diversity through metagenomic mining and machine learning [PDF]
Recognition of protospacer adjacent motifs (PAMs) is crucial for target site recognition by CRISPR–Cas systems. In genome editing applications, the requirement for specific PAM sequences at the target locus imposes substantial constraints, driving ...
Tao Fang +9 more
doaj +2 more sources
Genotype-specific transcriptomic response to drought stress in potato cultivars modulated by microbial biostimulants [PDF]
Background Drought is a major abiotic stress that significantly limits potato productivity and tuber quality. Microbial biostimulants have emerged as promising tools to improve crop resilience and promote sustainable agriculture.
Rachele Tamburino +7 more
doaj +2 more sources
The second “Philippic” of Cicero and the image of Mark Antony in the ancient authors works [PDF]
The article examines the influence of Cicero’s second “Philippic” on the formation of the image of Mark Antony in the writings of ancient authors, primarily Plutarch.
Smykov, Evgeniy Vladimirovich
doaj +1 more source
Stochastic Model Driven Performance and Availability Planning for a Mobile Edge Computing System
Mobile Edge Computing (MEC) has emerged as a promising network computing paradigm associated with mobile devices at local areas to diminish network latency under the employment and utilization of cloud/edge computing resources.
Carlos Brito +7 more
doaj +1 more source
Phytanic acid, an inconclusive phytol metabolite: A review
Phytanic acid (PA: 3,7,11,15-tetramethylhexadecanoic acid) is an important biometabolite of the chlorophyll-derived diterpenoid phytol. Its biological sources (occurrence) and ADME (absorption, distribution, metabolism, and elimination) profile are well ...
Muhammad Torequl Islam +5 more
doaj +1 more source
New records of the invasive mollusk Melanoides tuberculata (Müller, 1774) (Gastropoda, Thiaridae) in the Brazilian Northeast [PDF]
Melanoides tuberculata (Müller, 1774) was recorded during field surveys of the malacofauna of Território Vale do Guaribas in Piauí state, northeastern Brazil.
Edson Lourenço da Silva +5 more
doaj +3 more sources
Tradução do excurso sobre o riso no diálogo Do orador (2.216-290), de Cícero, apresentado pelo personagem Gaio Júlio César Estrabão Vopisco.
Adriano Scatolin +1 more
doaj +1 more source
Rethinking Ethos: A Comparative Analysis of Persuasive Character Building in Classical Antiquity through the Lenses of Aristotle, Cicero, and Quintilian [PDF]
This text aims to reexamine the role of ethos in persuasion through a comparative analysis of the viewpoints of the great classical rhetoricians Aristotle, Cicero, and Quintilian.
Zhuang Ganlin
doaj +1 more source
To discover driver fusions beyond canonical exon-to-exon chimeric transcripts, we develop CICERO, a local assembly-based algorithm that integrates RNA-seq read support with extensive annotation for candidate ranking.
Liqing Tian +20 more
doaj +1 more source
Divulgação científica sobre os fósseis de Picos, Piauí
O município de Picos, na mesorregião sudeste do Estado do Piauí, Brasil, destaca-se pela grande diversidade fossilífera, representada principalmente por fósseis marinhos com idade em torno de 380 milhões de anos, pertencentes ao período geológico ...
Joceane Layane Rodrigues de Moura +3 more
doaj +1 more source

