Results 211 to 220 of about 1,168,282 (300)

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

open access: yesAdvanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao   +11 more
wiley   +1 more source

Multi-Institutional Registry of Large Bowel Cancer in Japan Conducted by the Japanese Society for Cancer of the Colon and Rectum in 2024: Cases Treated in 2016. [PDF]

open access: yesJ Anus Rectum Colon
Kobayashi H   +9 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

open access: yesAdvanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai   +12 more
wiley   +1 more source

Thapsigargin enhanced chemotherapeutic sensitivity of irinotecan in the inflammation-induced colorectal cancer model in mice. [PDF]

open access: yesSci Rep
Baruah S   +8 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai   +13 more
wiley   +1 more source

The Second Dimension of Democracy: The People and Their Constitution

open access: yesBaltic Journal of Law & Politics, 2009
Colón-Rios Joel
doaj   +1 more source

Helping Hands or Comforting the Soul?

open access: yesChristian Journal for Global Health, 2014
Maria Colon-Gonzalez
doaj   +1 more source

Proteogenomic characterization of human colon and rectal cancer

open access: yesNature, 2014
Bing Zhang   +78 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy