Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Multi-Institutional Registry of Large Bowel Cancer in Japan Conducted by the Japanese Society for Cancer of the Colon and Rectum in 2024: Cases Treated in 2016. [PDF]
Kobayashi H +9 more
europepmc +1 more source
Alergias e intolerâncias alimentares - Novas perspetivas [PDF]
Helena Maria Carvalho do Monte
core
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
Thapsigargin enhanced chemotherapeutic sensitivity of irinotecan in the inflammation-induced colorectal cancer model in mice. [PDF]
Baruah S +8 more
europepmc +1 more source
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai +13 more
wiley +1 more source
The Second Dimension of Democracy: The People and Their Constitution
Colón-Rios Joel
doaj +1 more source
Helping Hands or Comforting the Soul?
Maria Colon-Gonzalez
doaj +1 more source
Nutritional Modulation of Melatonin-SIRT1 Signaling by Octanoic Acid-Rich Enteral Nutrition Protects Against Radiation-Induced Intestinal Injury. [PDF]
Zhou C, Li X, Xing C, Cao C.
europepmc +1 more source
Proteogenomic characterization of human colon and rectal cancer
Bing Zhang +78 more
semanticscholar +1 more source

