Results 241 to 250 of about 621,793 (253)

Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Acid sphingomyelinase deficiency (ASMD) is a rare debilitating lysosomal storage disease resulting in multisystemic disease manifestations, significant disease burden, and early mortality for some individuals. Enzyme replacement therapy (ERT) with olipudase alfa (Xenpozyme) is the first disease‐specific treatment indicated for noncentral ...
Melissa P. Wasserstein, Carla E. Hollak, Antonio Barbato, Renata C. Gallagher, Roberto Giugliani, Norberto Bernardo Guelbert, Julia B. Hennermann, Takayuki Ikezoe, Robin Lachmann, Olivier Lidove, Paulina Mabe, Eugen Mengel, Maurizio Scarpa, Ebubekir Senates, Michel Tchan, Beth L. Thurberg, Jesus Villarrubia, Nicole M. Armstrong, Shashi Bhushan, Yong Kim, Monica Kumar   +20 more
wiley   +1 more source

Modulation of inflammasome components in patients with heart failure using oral nutritional supplements: investigating the molecular mechanisms beyond the clinical benefit. [PDF]

Eur J Nutr
Herrera-Martínez AD, Hermán-Sánchez N, G-García ME, Muñoz-Jiménez C, Pérez-Gómez JM, Montero-Hidalgo AJ, López-Aguilera J, González-Manzanares R, Gálvez-Moreno MÁ, Molina-Puerta MJ, Luque RM.   +10 more
europepmc   +1 more source

Esterification enhances carotenoid retention during bread‐making

Journal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4312-4319, May 2026.
Abstract BACKGROUND Carotenoids are plant‐derived antioxidants that contribute to human health and represent key quality traits in wheat‐based foods. However, they are highly unstable and prone to degradation during processing. Xanthophyll esterification has been identified as a natural mechanism that enhances carotenoid stability during grain storage.
María D Requena‐Ramírez, Cristina Rodríguez‐Suárez, Dámaso Hornero‐Méndez, Sergio G Atienza   +3 more
wiley   +1 more source

Ribcage Morphology in Native South American Populations From Different Altitudes: Insights From a Global Comparative Framework. [PDF]

Am J Hum Biol
López-Rey JM, D'Angelo Del Campo MD, Bettera Marcat G, Arrieta M, Fabra M, Salega S, Mercolli P, Seldes V, García-Martínez D, Bastir M.   +9 more
europepmc   +1 more source

Weaving for action: Transformative change in biodiversity monitoring

People and Nature, Volume 8, Issue 5, Page 1007-1020, May 2026.
Abstract The Post‐2020 Kunming‐Montreal Biodiversity Framework aims to drive transformative change to halt biodiversity loss. To track progress toward its goals and targets, a dedicated monitoring framework has been established. The current biodiversity monitoring framework relies on a set of indicators developed through a unidirectional process of ...
Carol X. Garzon‐Lopez, Laura M. Bellis, Camilo Castillo, Tahani Nadim, Duccio Rocchini, Koenraad Van Meerbeek, Hakon Stokland, Esther Turnhout, Margaret Gold, Anne Beaulieu   +9 more
wiley   +1 more source

Short-term effects of craniosacral therapy and rhythmic movement training on developmental assessment scores and primitive reflex expression in typically developing children: a randomized controlled trial. [PDF]

Front Public Health
León-Bravo G, Cabello-Jurado C, Peña-Toledo MÁ, Cantarero-Carmona I.   +3 more
europepmc   +1 more source

Biomechanical assessment of dressage Spanish horses through accelerometry and the immediate effects of a single capacitive resistive electrical transfer session. [PDF]

BMC Vet Res
Calle-González N, Rivero JL, Argüelles D, Requena F, Muñoz A.   +4 more
europepmc   +1 more source

Biphasic Regulation of Epithelial Antimicrobial Peptides During <i>Candida albicans</i> Vaginal Infection: Distinct Contributions of NLRP3/IL-1β and IL-17RA Pathways to β-Defensin-1 and -3 Expression. [PDF]

J Fungi (Basel)
Angiolini SC, Rodriguez E, Manzone-Rodriguez C, Icely PA, Miró MS, Riera FO, Iribarren P, Caeiro JP, Sotomayor CE.   +8 more
europepmc   +1 more source

Functional Interplay Between Upper Loop Reentry and Clockwise Cavotricuspid Isthmus-Dependent Flutter in a Non-surgical Right Atrium: A Case of Dual-Loop Macroreentry. [PDF]

Cureus
Sosa-Alvarez CJ, Cordoba-Alvarado D, Mariscal-Diaz OY, Loza-Nuño JA.   +3 more
europepmc   +1 more source