Results 91 to 100 of about 126,902 (239)
Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
Revisión sistemática de las técnicas lamelares del trasplante de córnea [PDF]
En el presente trabajo fin de grado realizamos una revisión sistemática de la literatura científica de las técnicas lamelares del trasplante de córnea, mostrando la evolución de dicha técnica a través del paso de los años y nuevos avances futuros ...
Sánchez Pérez, Antonio +2 more
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Relevância da biomecânica da córnea no glaucoma
, 2012 Relato de caso de uma paciente, com córnea espessa, por distrofia de Fuchs em fase inicial, ainda com transparência corneana preservada (edema corneano subclínico), associado à pressão intraocular (PIO) normal por tonometria de aplanação de Goldman (TAG),
Renato Ambrósio Jr +2 more
core +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Advanced Science, EarlyView.Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Afecções de córnea em felinos : estudo retrospectivo (2007 a 2017) [PDF]
, 2017 A córnea dos felinos domésticos pode apresentar afecções únicas da espécie, além de demonstrar alto potencial para abrigar vírus patogênicos. O objetivo deste estudo foi avaliar a casuística das afecções de córnea em felinos atendidos no Serviço de ...
Macedo, Melina Bárbbara Bender
core +1 more source
Accidents in the Chemical Industry: A Scoping Review Focused on Causal Factors
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Although occupational safety in the chemical industry is an area of ongoing research worldwide, chemical incidents continue to occur, indicating the need to review the causes, assist in safety management, and identify problems in the quality of reporting. Methods A systematic search of studies published in English between January 1,
Željka Babić +7 more
wiley +1 more source
Comparativa de válvula de Ahmed mal posicionada. Estudio mediante Swept- Source A-OCT
Revista Mexicana de Oftalmología, 2022 Javier Lacorzana +1 more
doaj +1 more source
Una producción córnea extraordinaria : Cuerno cutáneo [PDF]
, 1907 A fines del año próximo pasado, llegó al mercado de lanares, ubicado en la estación Tablada, procedente de una estancia del partido de General Pintos, la oveja cuya fotografía se reproduce y que presentaba un enorme cuerno cutáneo en la parte media de la
Reibel, Jorge
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Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source