Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Spatial distribution and broad-band spectral characteristics of the diffuse X-ray background, 0.1 - 1.0 keV [PDF]
Preliminary maps covering more than 85 percent of the sky are presented for three energy bands: the B band, the C band, and the M band. The study was undertaken to find evidence that most of the diffuse X-ray background at energies less than 1 keV is ...
Burrows, D. N. +3 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Reconfigurable antennas are key candidates for modern wireless communicating devices to perform multiple wireless operations on various frequencies. This paper is introducing a compact yet efficient design of frequency reconfigurable TX-Shaped monopole ...
Sadiq Ullah
doaj
ACCURATE LABORATORY WAVELENGTHS OF THE e 3 Σ – (ν′ = 5) – X 1 Σ + (ν″ = 0) BAND OF 12 C 16 O [PDF]
G. D. Dickenson +4 more
openalex +1 more source
The Design, Validation, and Analysis of Surface-Based S-band and C-band Polarimetric Scatterometers
Chad Baldi
openalex +1 more source
Telecom wavelength single quantum dots with very small excitonic fine-structure splitting
We report on molecular beam epitaxy growth of symmetric InAs/InP quantum dots (QDs) emitting at telecom C-band (1.55 $\mu$m) with ultra-small excitonic fine-structure splitting of ~2 $\mu$eV.
Benyoucef, Mohamed +2 more
core +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Molecular Cytogenetic Characterization of C-Band-Positive Heterochromatin of the Greater Long-Tailed Hamster (Tscherskia triton, Cricetinae) [PDF]
Eikichi Kamimura +4 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source

