Results 51 to 60 of about 7,211,500 (239)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

EPIDEMIOLOGICAL ASSESSMENT OF THE PREVALENCE OF GASTROESOPHAGEAL REFLUX DISEASE IN SLOVENIA

Zdravniški Vestnik, 2002
Background. No adequate epidemiological study of gastroesophageal reflux disease (GERD) has as yet been conducted in Slovenia. This epidemiological study provided data on the frequency of upper gastrointestinal tract endoscopies in a limited geographic ...
Gregor Pleterski, Marijan Ivanuša, Jože Drinovec, Aleš Mrhar   +3 more
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Desafíos del proceso de construcción de paz para la Policía Nacional de Colombia

Revista Criminalidad, 2015
Se desarrolla un análisis de los puntos convergentes derivados de las deliberaciones teórico-prácticas suscitadas en el marco del V Seminario Internacional de Inteligencia Estratégica y Prospectiva, con el propósito de reflexionar alrededor de algunas ...
Luisa Fernanda Pedraza Uribe, Artur Oswaldo Villamizar Moreno, Zuly Andrea Ortiz Arcos   +2 more
doaj   +1 more source

Comment on: “Challenging the Odds: Long‐Term Survival in Pediatric Diffuse Midline Glioma With H3 K27M and BRAF V600 Co‐Mutations Treated With Upfront Radiotherapy and Targeted Therapy”

Pediatric Blood &Cancer, EarlyView.
Natália Dassi, Andrea Maria Cappellano
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Advanced artificial intelligence in piRNA and PIWI-like protein research: A systematic review of recurrent neural networks, long short-term memory, and emerging computational techniques

Biomédica: revista del Instituto Nacional de Salud
Introduction. PIWI-interacting RNAs are small and non-coding RNAs involved in gene regulation and transposable element repression, emerging as critical biomarkers and therapeutic targets in oncology. Advances in artificial intelligence, such as recurrent
Jheremy Sebastián Reyes, Jhonathan David Guevara, Laura Tatiana Picón, Iris Lorena Sánchez, Libia Andrea Gaona, María Paula Montoya, Luis Eduardo Pino   +6 more
doaj   +1 more source

Registros administrativos de policía para la consolidación de cifras de criminalidad en Colombia

Revista Criminalidad, 2015
La Policía Nacional de Colombia desarrolla la operación estadística “Conductas y servicios de policía”, para tener insumos que permitan la formulación de políticas públicas en seguridad y seguimiento permanente del impacto del servicio de policía; esta ...
Julián Ricardo Buitrago Cubides, Jair David Rodríguez Ortega, Pedro Aleksander Bernal Urrutia   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source