Results 101 to 110 of about 3,071,324 (279)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Beyond enterprise resource planning projects: innovative strategies for competitive advantage [PDF]

open access: yes, 1999
A rapidly changing business environment and legacy IT problems has resulted in many organisations implementing standard package solutions. This 'common systems' approach establishes a common IT and business process infrastructure within organisations and
Holland, C, Kawalek, P, Light, BA
core   +1 more source

Radiative Properties of Pair-instability Supernova Explosions

open access: yes, 2012
We present non-LTE time-dependent radiative-transfer simulations of pair-instability supernovae (PISNe) stemming from red-supergiant (RSG), blue-supergiant (BSG) and Wolf-Rayet (WR) star rotation-free progenitors born in the mass range 160-230Msun, at 10^
Blondin, Stéphane   +4 more
core   +3 more sources

Light fragments from (C + Be) interactions at 0.6 GeV/nucleon

open access: yesEPJ Web of Conferences, 2016
Nuclear fragments emitted at 3.5° in 12C fragmentation at 0.6 GeV/nucleon have been measured. The spectra obtained are used for testing the predictions of four ion-ion interaction models: INCL++, BC, LAQGSM03.03 and QMD as well as for the comparison with
Abramov B.M.   +12 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Dynamics of carbon dioxide exchange of a wheat community grown in a semi-closed environment [PDF]

open access: yes
A wheat (Triticum aestivum Yecora Rojo) community was grown in the semi-closed conditions of the NASA/KSC Biomass Production Chamber (BPC). Experiments were conducted to determine whole community carbon dioxide exchange rates as influenced by growth and ...
Corey, Kenneth A.
core   +1 more source

Visible light-driven C−H activation and C–C coupling of methanol into ethylene glycol

open access: yesNature Communications, 2018
Direct transformation of methanol into two- or multi-carbon compounds is extremely attractive but remains a challenge. Here, the authors report an efficient photocatalytic route to the transformation of methanol into ethylene glycol and hydrogen over a ...
Shunji Xie   +10 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Monitoring-Oriented Programming: A Tool-Supported Methodology for Higher Quality Object-Oriented Software [PDF]

open access: yes, 2004
This paper presents a tool-supported methodological paradigm for object-oriented software development, called monitoring-oriented programming and abbreviated MOP, in which runtime monitoring is a basic software design principle.
Chen, Feng   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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