Results 181 to 190 of about 3,071,324 (279)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Efficacy of an upper room ultraviolet-C (UV-C) technology versus far UV-C light technologies in reducing aerosolized bacteriophage MS2. [PDF]

Antimicrob Steward Healthc Epidemiol
Memic S, Cadnum JL, Donskey CJ.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Identification of cauliflower cultivars that differ in susceptibility to Verticillium longisporum using different inoculation methods [PDF]

, 2005
Debode, Jane, DECLERCQ, BARBARA, Höfte, Monica   +2 more
core   +2 more sources

Characterization of Self-Cured Silicone Oils for Encapsulation of Ultraviolet-C Light-Emitting Diodes. [PDF]

Polymers (Basel)
Qiu X, Yu Q, Cheng Y, Lo JCC, Lee SR.
europepmc   +1 more source

Evaluation of 2 Ultraviolet-C Light Boxes for Decontamination of N95 Respirators. [PDF]

Pathog Immun, 2021
Cadnum JL, Pearlmutter BS, Li DF, Jencson AL, Scott JG, Charnas IC, Donskey CJ.   +6 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

UV-C Light, an Example of Application for Air Sanification

Memorie della Società Astronomica Italiana, 2022
MACCHI, Alberto, LOMBINI, Matteo, BIANCO, ANDREA, DIOLAITI, Emiliano, CORTECCHIA, Fausto, LESSIO, Luigi, FRANGIAMORE, Michele, MALAGUTI, Giuseppe, PARESCHI, Giovanni, Calandrino Van Kleef, Natasha   +9 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Enhancing the Quality of Indoor-Grown Basil Microgreens with Low-Dose UV-B or UV-C Light Supplementation. [PDF]

Int J Mol Sci
Skowron E, Trojak M, Pacak I, Węzigowska P, Szymkiewicz J.   +4 more
europepmc   +1 more source