Results 171 to 180 of about 20,395,316 (257)

PSMF1 Variants in a German Parkinson's Disease Cohort

Movement Disorders, EarlyView.
Carolin Gabbert, Christoph Much, Alicia Wenghöfer, André Fienemann, Susen Schaake, Theresa Lüth, Max Borsche, Norbert Brüggemann, Christine Klein, Joanne Trinh   +9 more
wiley   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf. [PDF]

Cell Death Dis, 2020
Xu Y, Sun T, Zeng K, Xu M, Chen J, Xu X, Zhang Z, Cao B, Tang X, Wu D, Kong Y, Zeng Y, Mao X.   +12 more
europepmc   +1 more source

Mg2+ Ions as Interfacial Charge Bridges for Enhanced Photocatalytic Hydrogen Evolution in Poly(Heptazine Imide)

Small, EarlyView.
Mg2+ confined within poly(heptazine imide) acts as a heterogenized interfacial charge bridge capable to couple synergistically the semiconductor with Pt co‐catalysts, thus enhancing hydrogen evolution. Through water polarization and hydroxide stabilization, a dynamic Mg2+‐OHδ−‐Hδ+‐Pt motif facilitates proton transfer and overcomes interfacial electron ...
Gabriel A. A. Diab, Vitor G. S. Pastana, Sara Stolfi, Rayse M. Ferreira, Izadora F. Reis, Marcos A. R. da Silva, Caio V. C. Ribeiro, Kathrin Küster, Piero Torelli, Paolo Ghigna, Viola Duppel, Maurizio Fagnoni, Sebastian Bette, Bruna R. Serino, Andre F. de Moura, Davide Ravelli, Bettina V. Lotsch, Ivo F. Teixeira   +17 more
wiley   +1 more source

The Rise of Layered Double Hydroxides (LDHs) in Hexavalent Chromium (Cr(VI)) Pollution Treatment: Performance, Optimization, and Challenges

Safety Science and Technology, EarlyView.
This article focus on the basic properties, adsorption processes, performance improvement strategies, and the facing challenges of LDHs. ABSTRACT Layered double hydroxides (LDHs), a class of inorganic materials with unique layered structures, exhibit significant potential in environmental remediation.
Wenqi Fan, Shuai Tian, Jiwen Lai, Zhiwu Min, Qingyang Qiu, Xian Li, Zuwen Liu   +6 more
wiley   +1 more source

Architecting and Industrializing Advanced Production and Manufacturing Systems for Critical Industries

Systems Engineering, EarlyView.
ABSTRACT Advanced production systems play a vital role in modern society. Such systems are developed and industrialized over multiple years and at great expense. The complexities of these systems are exacerbated in the case of metal additive manufacturing, which involves numerous process variables and relies on various auxiliary systems.
Duncan W. Gibbons, Andre F. van der Merwe   +1 more
wiley   +1 more source

A Multi‐Sequence Adversarial Fusion U‐Net for Brain Tumor Image Segmentation

IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
In the field of brain tumor image segmentation, in order to avoid the impact of insufficient number of training samples, the method of fusing multi‐modal MRI information before segmentation is widely used. However, when fusing different modal features, existing methods only add fixed weights to the features of each modality, resulting in insufficient ...
Jie Wang, Jinglu Hu
wiley   +1 more source

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease (ESRD) in Colombian Patients

Environmental Toxicology, EarlyView.
ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez, Juliana Lago, Carlos Trillos, Marcela Varona, Leonardo Briceño, Ruth Marien Palma, Sonia M. Díaz, Gilma Hernández, Eliana M. Téllez, Juan Sebastián Aguilar, Daniela Castellanos, Xavier Martínez, Estefanía Zapata, Alix Rocio Barrios, Ignacio Villanueva, Michael R. Fonseca, Helena Groot   +16 more
wiley   +1 more source

Biopolymer‐Based Polyelectrolyte Nanoplatforms for Targeted Photodynamic Therapy of Breast Cancer

VIEW, EarlyView.
Illustration of the synthesis of 5‐aminolevulinic acid loaded chitosan‐sericin polyelectrolyte nanoparticles (CSSN/ALA NPs) using the Flash nanocomplexation (FNC) technique and their potential in photodynamic therapy (PDT) against breast cancer (BC). Abstract Nanomedicine has reshaped healthcare, especially in targeted drug delivery systems (DDSs) and ...
Athira Narayanan, Benedetta di Chiara Stanca, Daniela Pinheiro, Laura Giannotti, Fabrizio Damiano, André Ferreira Moreira, Sónia Miguel, Leonardo Lamanna, Eleonora Stanca, Maria Grazia Raucci, Gianpiero Colangelo, Luisa Siculella, Alessandro Sannino, Paula Coutinho, Christian Demitri   +14 more
wiley   +1 more source