Results 141 to 150 of about 20,673,683 (288)

Canal Through Canal Fulton 2

open access: yes
One black and white photographic print of the Ohio and Erie Canal running through Canal Fulton in Stark County, Ohio. Houses line the left side of the canal and a road runs along the right side where it leads into a parking lot. Trees stand on both sides
Canal Society of Ohio
core  

The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment

open access: yesAdvanced Science, EarlyView.
The CXCL5/CXCR2 axis directly inhibits ferroptosis in ICC cells by activating the NF‐κB/PTGS2 pathway. Meanwhile, the CXCL5/CXCR2 axis recruits N2 TANs, and the activated PTGS2 promotes the secretion of TNF‐α from the recruited N2 TANs via the CCL2/CCL7/CCR2 pathway, thereby activating the NF‐κB/PTGS2 axis and forming a positive feedback loop, which ...
Chanqi Ye   +17 more
wiley   +1 more source

Canal Through Canal Fulton 1

open access: yes
One color photographic print of the Ohio and Erie Canal running through Canal Fulton in Stark County, Ohio. The canal can be seen on the right while a grass field can be seen on the left.
Canal Society of Ohio
core  

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

Canal Boat Ride

open access: yes
One black and white photographic print of several people on the stern of a canal boat as it flows down a canal, probably the Ohio and Erie Canal in Coschocton County, Ohio.
Canal Society of Ohio
core  

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Repair Boat on Canal

open access: yes
One black and white photographic print of a canal boat called the Repair Boat docked in the canal, probably the Ohio and Erie Canal in Scioto County, Ohio.
Canal Society of Ohio
core  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Canal Boat Under Bridge

open access: yes
One black and white photographic print of a canal boat passing under a bridge on a canal, probably the Ohio and Erie Canal in eastern Ohio. A person can be seen standing on top of the boat while several buildings can be seen lining the bank of the canal ...
Canal Society of Ohio
core  

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