Results 201 to 210 of about 20,673,683 (288)

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

C-Shaped Root Canal Morphology in Mandibular Posterior Teeth-A Retrospective CBCT Study Based on Two Classification Systems. [PDF]

Diagnostics (Basel)
Mirza MB, Abdulwahed A, AlShehri A, AlQahtani AR, Chawre M, AlQasem O, AlBader S, AbuelQomsan MAS, AlMufleh LS, AlMokhatieb A.   +9 more
europepmc   +1 more source

Unidentified Canal Lock Remains 6

One black and white photographic slide of an unidentified canal lock on a canal, probably the Ohio and Erie Canal in eastern Ohio. The lock gate is closed and water flows through the structure.
Canal Society of Ohio
core  

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

Pedestrian Bridge Over Canal

One color photographic print of a pedestrian bridge running over the Ohio and Erie Canal in Canal Fulton in Stark County, Ohio.
Canal Society of Ohio
core  

A Neutrophil Membrane‐Encapsulated Pd/hCeO2 Nanoformulation for Alleviating Age‐Dependent Perioperative Neurocognitive Disorders

Advanced Science, EarlyView.
This study reports a neutrophil membrane‐encapsulated Pd/hCeO2 nanozyme (PCN) for targeted treatment of perioperative neurocognitive disorders (PND) in aged mice. PCN inhibits glycolysis‐driven microglial activation and neuroinflammation, improves mitochondrial respiration, and maintains blood‐brain barrier integrity and synaptic function, ultimately ...
Lili Huang, Jiahui Cheng, Huan Xu, Qiang Zhang, Xiao Zhang, Ye Liu, Yizhe Zhang, Wanbing Dai, Zhi Xiong, Linghuan Guo, Lingling Xu, Wen Wang, Xin Xu, Yan Zhou, Weifeng Yu, Bo Li, Diansan Su, Daxiang Wen   +17 more
wiley   +1 more source

Successful orthograde treatment of dens invaginatus Type 3 with a main C-shaped canal based on cone-beam computed tomography evaluation. [PDF]

J Conserv Dent, 2016
Solomonov M, Itzhak JB, Levin A, Katzenell V, Shemesh A.   +4 more
europepmc   +1 more source

Canal Fulton Muzzle Loader

One color photographic print of the Muzzle Loader firing range in Canal Fulton in Stark County, Ohio. A mural painting on the side of the building depicts a canal boat on the canal as a road runs through the ...
Canal Society of Ohio
core  

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source

Unusual Root Canal Morphology in Mandibular Molars: A Case Series. [PDF]

Cureus
Mohan S, Chaudhury A, Thomas G, Jose S, Aboobacker S.   +4 more
europepmc   +1 more source