Abstract Aims The guideline‐directed medical therapy (GDMT) sequencing strategy for patients with heart failure (HF) and reduced ejection fraction (HFrEF) underwent a paradigm shift with the 2021 ESC HF guidelines, from stepwise escalation to rapid simultaneous initiation of quadruple therapy.
Kristian Berge+12 more
wiley +1 more source
Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm. [PDF]
Aubdool AA+17 more
europepmc +1 more source
Elevated N-terminal pro C-type natriuretic peptide is associated with mortality in patients undergoing transcatheter aortic valve replacement. [PDF]
Hu P+12 more
europepmc +1 more source
Implementation of guidelines for intravenous iron therapy in heart failure patients
Abstract Aims We aim to evaluate the implementation of the 2021 ESC Guidelines regarding screening and treatment of iron deficiency in patients with heart failure (HF) at Karolinska University Hospital. Methods and results Patients with left ventricular ejection fraction (LVEF) < 50% and New York Heart Association (NYHA) class II–IV who visited ...
Milou Gamage+5 more
wiley +1 more source
Optimizing C-Type Natriuretic Peptide and Receptor Expression Analysis with Droplet Digital™ PCR: Advancing Biomarker Discovery for Brugada Syndrome? [PDF]
Cabiati M+13 more
europepmc +1 more source
Abstract Aims Most proteomic analyses in patients with heart failure (HF) focus on the stable ambulatory setting; pathways that drive acute decompensated heart failure (ADHF) are largely uncharacterized. We aimed to examine the associations of cardiometabolic proteins with HF rehospitalization, mortality and diuretic response in patients with ADHF ...
Kenneth T. Hubbell+8 more
wiley +1 more source
C-Type Natriuretic Peptide Plays an Anti-Inflammatory Role in Rat Epididymitis Induced by UPEC. [PDF]
Mei C+5 more
europepmc +1 more source
C-Type Natriuretic Peptide Forms in the Ovine Fetal and Maternal Circulations: Evidence for Independent Regulation and Reciprocal Response to Undernutrition [PDF]
Timothy C. R. Prickett+6 more
openalex +1 more source
Abstract Chronic kidney disease (CKD) and chronic heart failure (HF) frequently coexist and, when comorbid, are associated with poorer outcomes. These two diseases have common risk factors, such as diabetes, obesity and hypertension, and common pathophysiological connected mechanisms, including inflammation, endothelial dysfunction, neurohormonal ...
Johann Bauersachs+2 more
wiley +1 more source