Results 21 to 30 of about 18,730,823 (160)

Gasdermin-D activation promotes NLRP3 activation and host resistance to Leishmania infection

open access: yesNature Communications, 2023
Here, de Sá et al. show that Gasdermin-D is transiently activated in Leishmania-infected macrophages and promotes NLRP3 inflammasome activation, but not cell death.
Keyla S. G. de Sá   +11 more
doaj   +1 more source

Comparison of venous plasma glycemia and capillary glycemia for the screening of type 2 diabetes mellitus in the Japanese-Brazilian community of Mombuca (Guatapará-SP)

open access: yesDiabetology & Metabolic Syndrome, 2010
Background To identify the most appropriate cut-off points of fasting glycemia for the screening of diabetes mellitus type 2 (DM2) with the comparison of the properties of capillary glycemia (CG) and venous blood plasma glycemia (PG) in a population of ...
Foss-Freitas Maria   +7 more
doaj   +1 more source

Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. To describe the epidemiology of superinfections (occurring > 48 hr after hospital admission) and their impact on the ICU and 28-day mortality in patients with coronavirus disease 2019 with acute respiratory distress syndrome, requiring ...
Liana Signorini, MD   +15 more
doaj   +1 more source

About a Tent: Accardi, Torino, Notizie

open access: yespiano b
Carla Accardi’s Tenda was first exhibited at the solo show that the artist held at the Galleria Notizie in 1966. In Turin Accardi had found a lively, open, and international cultural milieu, and a positive dialogue with several young artists ...
Claudio Zambianchi
doaj   +1 more source

Determinação voltamétrica de metais em águas e fluidos biológicos empregando mineralização de amostras com radiação ultravioleta Voltammetric determination of metals in waters and biological fluids using sample mineralization with ultraviolet radiation

open access: yesQuímica Nova, 2008
This work describes the optimization of pretreatment steps for the destruction of organic matter in samples of waters and biological fluids, by using an UV irradiation system with a high power UV radiation source (400 W).
Leandro M. de Carvalho   +10 more
doaj   +1 more source

Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells

open access: yeseLife, 2022
COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of macrophages allows this cell type to promote pathogen elimination and inflammation or suppress ...
Ana CG Salina   +42 more
doaj   +1 more source

Detection of sputum cofilin-1 as indicator of malignancy

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples.
M.P. Rangel   +11 more
doaj   +1 more source

Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model

open access: yesRespiratory Research, 2023
Background COVID-19 is characterized by severe acute lung injury, which is associated with neutrophil infiltration and the release of neutrophil extracellular traps (NETs). COVID-19 treatment options are scarce.
Flavio P. Veras   +15 more
doaj   +1 more source

Influência da forma dos agregados miúdos nas propriedades do concreto

open access: yesRevista IBRACON de Estruturas e Materiais
Os agregados miúdos utilizados na produção de concretos são basicamente as areias naturais provenientes dos leitos dos rios e os agregados artificiais oriundos da britagem de rocha. A principal diferença entre estes dois agregados está no formato de seus
F. Fabro   +3 more
doaj   +1 more source

P57 | MELFLUFEN IS EFFECTIVE AND SAFE IN MULTIPLE MYELOMA PATIENTS WITH SEVERE RENAL IMPAIRMENT

open access: yesHaematologica
Multiple myeloma (MM) is often complicated with renal insufficiency (RI) which adversely influences the prognosis. The incidence of RI in MM patients ranges from 20% to 50% and is primarily due to light chains deposition in the kidney.
C. Bellofiore   +9 more
doaj   +1 more source

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