Results 61 to 70 of about 31,042 (188)

Modular Molecular Design and Self‐Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels

Small, EarlyView.
Saccharide‐appended cyclic dipeptides are designed and developed as building blocks for glycosidase‐responsive supramolecular hydrogels. Their aqueous self‐assembly enables β‐galactosidase‐triggered gel‐to‐sol and neuraminidase‐triggered sol‐to‐gel transition systems, highlighting their potential as glycosidase‐responsive soft materials for biomedical ...
Shintaro Sugiura, Ryuta Tanaka, Sayuri L. Higashi, Aya Shibata, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Masato Ikeda   +6 more
wiley   +1 more source

Detection of Clostridium perfringens type C in pig herds following disease outbreak and subsequent vaccination

, 2012
Immunisation of sows using Clostridium perfringens type C toxoid vaccines is recommended to prevent necrotising enteritis (NE) on pig breeding farms. Absence of disease, however, oftentimes leads to the false assumption of pathogens being eradicated. The
M. G. Doherr, Posthaus, H., H. Posthaus, M. Wyder, A. Candi, K. Schäfer, Schäfer, K., Gobeli, S., Zehnder, B, S. Gobeli, Doherr, M.G., B. Zehnder, Wyder, M., Zimmermann, W., Candi, A., W. Zimmermann   +15 more
core   +1 more source

Efficacy of both antibiotic and probiotic for control of necrotic enteritis in chickens experimentally [PDF]

Egyptian Journal of Animal Health
Clostridium perfringens (C. perfringens) is the pathogenic bacterium caused necrotic enteritis (NE) which is the most threatening problem in poultry sector.
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source

Rapid cytopathic effects of Clostridium perfringens beta-toxin on porcine endothelial cells

, 2010
Clostridium perfringens type C isolates cause fatal, segmental necro-hemorrhagic enteritis in animals and humans. Typically, acute intestinal lesions result from extensive mucosal necrosis and hemorrhage in the proximal jejunum.
Sutter, E, Gurtner, C, Posthaus, H, Frey, J, von Schubert C.,, Wyder, M, Zeeh, F, Popescu, F   +7 more
core   +1 more source

Clostridium perfringens in the Intestine: Innocent Bystander or Serious Threat?

Microorganisms
The Clostridium perfringens epidemic threatens biosecurity and causes significant economic losses. C. perfringens infections are linked to more than one hundred million cases of food poisoning annually, and 8–60% of susceptible animals are vulnerable to ...
Xuli Ba, Youshun Jin, Xuan Ning, Yidan Gao, Wei Li, Yunhui Li, Yihan Wang, Jizhang Zhou   +7 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies

, 2013
Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Titball, R.W., Kokkinidou, Maria C., Richard W. Titball, Bokori-Brown, M., Kokkinidou, M.C., Claire E. Naylor, Fernandes da Costa, S.P., Moss, David S., Titball, Richard W., Monika Bokori‐Brown, Maria C. Kokkinidou, David S. Moss, Basak, Ajit K., Bokori-Brown, Monika, Cole, Ambrose R., Sérgio Fernandes da Costa, Naylor, Claire E., Ambrose R. Cole, Fernandes da Costa, Sérgio P., Christos G. Savva, Ajit K. Basak, Savva, Christos G.   +21 more
core   +1 more source

Galleria mellonella Infection Model Identifies Both High and Low Lethality of Clostridium perfringens Toxigenic Strains and Their Response to Antimicrobials

Frontiers in Microbiology, 2019
Research progress into mechanisms of the anaerobe Clostridium perfringens and associated diseases has been frustrated by the lack of reliable infection models.
Sammy Kay, Sammy Kay, Joseph Edwards, Joseph Edwards, Joseph Brown, Ronald Dixon   +5 more
doaj   +1 more source