Results 171 to 180 of about 82,467 (245)

How do strategic leaders frame corporate purpose? Investigating competing frames and framing approaches in executive discourse

open access: yesEuropean Management Review, EarlyView.
Abstract Corporate purpose is gaining momentum in contemporary business communities, yet it often appears shrouded in ambiguity. Although research is growing in popularity, the analysis of corporate purpose from the perspective of strategic leaders remains an unexplored domain.
Chiara Pantalena   +3 more
wiley   +1 more source

Consistent supra-molecular motif of <i>C</i>(7) O-H⋯O hydrogen-bonded chains and different local symmetries in three iso-indole-4-carb-oxy-lic acid derivatives. [PDF]

open access: yesActa Crystallogr E Crystallogr Commun
Alekseeva KA   +5 more
europepmc   +1 more source

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

open access: yesThe FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna   +17 more
wiley   +1 more source

Crystal structure and Hirshfeld surface analysis of (<i>E</i>)-2-[(anthracen-9-yl-methyl-idene)amino]-4-nitro-aniline. [PDF]

open access: yesActa Crystallogr E Crystallogr Commun
Benkirane S   +5 more
europepmc   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

open access: yesThe FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova   +12 more
wiley   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

open access: yesThe FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova   +6 more
wiley   +1 more source

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