Results 51 to 60 of about 82,467 (245)

Cyprinid Herpesvirus 2 miR-C12 Attenuates Virus-Mediated Apoptosis and Promotes Virus Propagation by Targeting Caspase 8

open access: yesFrontiers in Microbiology, 2019
DNA viruses, most notably members of the herpesvirus family, generally encode miRNAs to mediate both virus and host genes expression. We previously demonstrated that Cyprinid herpesvirus 2 (CyHV-2) encodes 17 miRNAs that are involved in innate immune ...
Jianfei Lu   +12 more
doaj   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation

open access: yesAngewandte Chemie, EarlyView.
The total synthesis of the bis‐indole alkaloid (−)‐owerreine has been accomplished by a diastereoselective [4+2] annulation between an enamine and an α,β−unsaturated indolenine precursor to form the 3‐spirocyclic tetrahydropyridine linkage of the natural product. DFT calculations allow an understanding of the mechanism of the key annulation.
Elisa Coll   +4 more
wiley   +2 more sources

Salt Water Drops Slide Faster: Ionic Modulation of Drop Friction

open access: yesAdvanced Science, EarlyView.
Salt ions markedly accelerate water drops on conductive substrates coated with nanometer‐thin hydrophobic layers. Across diverse electrolytes and surfaces, higher ion concentration consistently lowers kinetic friction by reducing contact angle hysteresis.
Dongho Shin   +6 more
wiley   +1 more source

Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma

open access: yesCancer Management and Research, 2020
Fabian Eberle, 1–4 Stefan Lautenschläger, 4 Rita Engenhart-Cabillic, 1, 3, 4 Alexandra D Jensen, 5 Barbara Carl, 6 Marco Stein, 7 Jürgen Debus, 1–3, 8–11 Henrik Hauswald 1–4, 8, 10, 11 1Department of Radiation Oncology,
Eberle F   +7 more
doaj  

In‐Wheel Piezoelectric DC Power Generator With Zero Resistive Torque

open access: yesAdvanced Science, EarlyView.
In this paper, we present a wheel‐shaped direct‐current piezoelectric generator (DC‐PG) that fundamentally overcomes these constraints by producing phase‐stable DC electricity directly from rolling motion. By embedding this system into suitcase wheels, we demonstrated a fully integrated real‐time location tracking system powered solely by mechanical ...
Hyun Soo Kim   +19 more
wiley   +1 more source

Design of Optical Transducer for Recognition of Biomolecular Interactions between Bacterial Lipopolysaccharides and Amino Acids

open access: yesAdvanced Science, EarlyView.
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi   +10 more
wiley   +1 more source

Trends and Patterns in Shared Accommodation in Europe and Serbia: What Do We Know So Far?

open access: yesBusiness Systems Research
Sharing economy is a socio-economic paradigm characterised by the collaborative utilisation of resources and services among individuals, facilitated through digital platforms. Shared accommodation attracts the attention of various stakeholders due to its
Maričić Milica   +3 more
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

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