Results 121 to 130 of about 393,712 (148)

Homozygous C3 deficiency: Detection of C3 by radioimmunoassay

Clinical Immunology and Immunopathology, 1977
Abstract A 5 10 12 - year-old girl with recurrent infections was found to have homozygous C3 deficiency. Family studies demonstrated that the pattern of inheritance was consistent with that of an autosomal codominant trait. C3 levels have ranged from 5 mg/100 ml (electroimmunoassay) to 1.7 μg/100 ml (radioimmunoassay) 2 years later.
A E, Davis, J S, Davis, A R, Rabson, S G, Osofsky, H R, Colten, F S, Rosen, C A, Alper   +6 more
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Effect of C3 Inactivator on Bound C3 Antigen

The Journal of Immunology, 1972
Abstract The effect of C3 inactivator (C3ina) in human EDTA plasma on C3 antigen bound to various immune complexes was determined. C3ina greatly decreased the amount of C3 bound to human erythrocytes sensitized with IgM anti-I cold agglutinin, and also decreased erythrocyte-bound C3 of a patient with deficiency of C3 inactivator, but had
E J, Leonard, T, Borsos
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C3 Glomerulopathy

2013
C3 glomerulopathy is a recent disease classification comprising several rare types of glomerulonephritis, including dense deposit disease (DDD) and C3 glomerulonephritis (C3GN). The most common histological feature in these diseases is the presence of glomerular deposition of C3 within the mesangium and along the glomerular basement membrane (GBM) in ...
Aude, Servais, Laure-Hélène, Noël, Véronique, Frémeaux-Bacchi, Philippe, Lesavre   +3 more
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Pure C3 modules

Asian-European Journal of Mathematics, 2023
Within the paper, we study the class of modules in which the direct sum of two disjoint summands that is a pure submodule is also a summand. This class of modules is considered [Formula: see text] modules, a generalization of [Formula: see text] modules. In addition to pure-injective and [Formula: see text] modules that belong to the class of [Formula:
Kaushal Gupta, Ashok Ji Gupta
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Inherited complement C3 deficiency: A defect in C3 secretion

European Journal of Immunology, 1994
AbstractThe molecular basis of inherited complement C3 deficiency in a 20‐year‐old newly diagnosed male patient was studied. Using an enzyme‐linked immunosorbent assay, the patient's C3 serum level was found to be approximately 7 μg/ml, which is less than 1 % of normal.
Y, Katz, L, Singer, R A, Wetsel, M, Schlesinger, Z, Fishelson   +4 more
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C3 nephritic factor associated with C3 glomerulopathy in children

Pediatric Nephrology, 2013
C3 glomerulopathy (C3G) is characterized by predominant C3 deposits in glomeruli and dysregulation of the alternative pathway of complement. Half of C3G patients have a C3 nephritic factor (C3NeF). C3G incorporated entities with a range of features on microscopy including dense deposit diseases (DDD) and C3 glomerulonephritis (C3GN).
Camille, Nicolas, Vincent, Vuiblet, Veronique, Baudouin, Marie-Alice, Macher, Isabele, Vrillon, Nathalie, Biebuyck-Gouge, Maud, Dehennault, Sophie, Gié, Denis, Morin, Hubert, Nivet, François, Nobili, Tim, Ulinski, Bruno, Ranchin, Maria Chiarra, Marinozzi, Stéphanie, Ngo, Véronique, Frémeaux-Bacchi, Christine, Pietrement   +16 more
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C3 Variants and Disease

Human Heredity, 1986
The distribution of C3 variants in dermatitis herpetiformis, thyroid cancer, spinal muscular atrophy, multiple sclerosis and psoriasis was studied, and also the Bf phenotype distribution in thyroid cancer. In thyroid cancer there was a significant deficit of heterozygotes for the C3 locus, a possible decrease in the C3F allele frequency and a ...
J E, Bernal, S S, Papiha, D F, Roberts
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C3 Activator in Agammaglobulinemia

International Archives of Allergy and Applied Immunology, 2009
C3 activator in sera of patients with agammaglobulinemia shows higher levels compared with age-matched healthy controls. This fact may be due to a compensatory function of the alternative pathway of the complement system to make up for the defect of production of antibody in these patients.
S, Nakajima, K, Nihei, Y, Hyodo
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Inhibitor of Human C3 Associated with Preparations of C3 Dissociated from C3-Zymosan Complex

The Journal of Immunology, 1969
Abstract Incubation of human serum with zymosan at 37°C, followed by removal of the zymosan residue by centrifugation, resulted in C3-zymosan complex. The C3-zymosan complex could be dissociated and C3 recovered in the eluate. Preparations of dissociated C3 did not contain the hemolytically active component of complement, C1 esterase, or
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C3 concentrations can be normal in patients with C3 glomerulopathy secondary to C3 nephritic factor

Journal of Clinical Pathology
C3 glomerulopathy (C3G) is a rare kidney disease caused by the glomerular deposition of C3 fragments secondary to alternative pathway complement dysregulation. C3 nephritic factors (C3Nef) are the most common acquired cause, and their detection has treatment and prognostic implications.
Hamish Anderson, Mark Van Voorthuizen, John O'Donnell, Sarah Beck   +3 more
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