Results 41 to 50 of about 4,189 (213)
Synthesis of a Truncated Analog of Amphidinol 3 Corresponding to the C21–C39/C52–C67 Section [PDF]
Chemistry Letters, 2017 As a part of structure–activity relationship studies to elucidate structure requirements for eliciting antifungal activity, an artificial analog of amphidinol 3 (AM3) was designed. A truncated analog corresponding to the C21–C39/C52–C67 section was synthesized by using Suzuki–Miyaura coupling and Julia–Kocienski olefination as key steps. An expeditious
Makoto Ebine +3 more
openaire +1 more source
International Journal of Urology, Volume 33, Issue 7, July 2026.ABSTRACT Objectives To characterize the temporal changes in perioperative systemic treatment patterns and postoperative mortality among Japanese patients with stage II–III muscle‐invasive bladder cancer (MIBC) undergoing radical cystectomy (RC) from 2013 to 2024.
Eiji Kikuchi +6 more
wiley +1 more source
Journal of Economics and ManagementAim/purpose – In line with the general trend of digitalization and changing customers’ needs and preferences, insurance companies have increasingly applied digital technology to their business.
Ćurak Marijana +2 more
doaj +1 more source
CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.Abstract This article provides updated global cancer statistics for the year 2024 based on the GLOBOCAN estimates of the International Agency for Research on Cancer. The authors describe national cancer incidence and mortality by world region and the Human Development Index and predict the burden in 2050 based on demographic trends.
Hyuna Sung +7 more
wiley +1 more source
The Meisenheimer Complex as a Paradigm in Drug Discovery: Reversible Covalent Inhibition through C67 of the ATP Binding Site of PLK1 [PDF]
Cell Chemical Biology, 2018 The polo kinase family are important oncology targets that act in regulating entry into and progression through mitosis. Structure-guided discovery of a new class of inhibitors of Polo-like kinase 1 (PLK1) catalytic activity that interact with Cys67 of the ATP binding site is described.
Pearson, Russell J. +5 more
openaire +4 more sources
Cancer, Volume 132, Issue 11, 1 June 2026.In 28,550 UK Biobank participants diagnosed with a single incident cancer, greater adherence to five of the lifestyle‐based WCRF/AICR Cancer Prevention Recommendations was associated with reduced risk of all‐cause mortality. These findings provide evidence to support the WCRF/AICR Cancer Prevention Recommendation to “After a cancer diagnosis, follow ...
Fiona C. Malcomson +6 more
wiley +1 more source
, 1990 We investigated the ability of Streptococcus mutans C67-1 to colonize simple bacterial plaques and the effects of age and stability of the pre-formed plaque on colonization resistance. Mixed plaques of Actinomyces viscosus WVU627, 'Streptococcus mitior'
C.J. Perrons, H.D. Donoghue
core +1 more source
Journal of Asian Architecture and Building Engineering, 2023 Burnt clay brick is one of the oldest and most widely used construction materials. The production of burnt clay bricks with various waste materials can help reduce the environmental hazards and improve brick performance at low manufacturing costs ...
Ali Murtaza Rasool +5 more
doaj +1 more source
International Journal of Cancer, Volume 158, Issue 11, Page 2829-2840, 1 June 2026.What's new? The establishment in 2014 of the population‐based cancer registry (PBCR) of Bhutan created new opportunities for understanding national cancer trends, which previously were anticipated from data in neighbouring countries. This study presents the first nine‐year summary of cancer patterns in Bhutan, derived from PBCR data. From 2014 to 2022,
Phub Tshering +9 more
wiley +1 more source
Stochastic key sector analysis: an application to a regional input–output framework
, 2008 R15, C15, C67,
Max Munday +3 more
core +1 more source