Results 111 to 120 of about 5,460 (176)

Association of uricemia with biochemical and dietary factors in human adults with metabolic syndrome genotyped to C677T polymorphism in the methylenetetrahydrofolate reductase gene Asociación de la uricemia con factores bioquímicos y dietéticos en humanos adultos con síndrome metabólico genotipados para el polimorfismo C677T en el gen metilenotetrahidrofolato reductasa

Nutrición Hospitalaria, 2011
It is suggested that hyperuricemia is a marker of cardiovascular risk in human adults with metabolic syndrome (MS). The C677T polymorphism in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR) is associated with hyperuricemia.
S. Kimi Uehara, G. Rosa
doaj  

Genotyping of MTHFR C677T by PCR-Sanger Sequencing.

, 2014
Sequencing chromatograms depicting the three genotypes of MTHFR C677T. The SNP positions are shown by black arrows. (A) Homozygous wild type CC (B) Heterozygous CT (C) Homozygous mutant TT.
Ritu Bhardwaj (603196), Akhtar Ali (603199), Mousumi Mutsuddi (323156), Prashaant Chaudhry (603198), Pradeep Kumar Bhaskar (603195), Abhishek Chandra (106753), Shashank Gupta (51589), Vidya Nair Chaudhry (603197), Ashim Mukherjee (53857)   +8 more
core   +1 more source

Meta-Analysis of Studies of the MTHFR C677T Variant and Stroke Risk in Chinese and Koreans

, 2013
Meta-Analysis of Studies of the MTHFR C677T Variant and Stroke Risk in Chinese and ...
Pankaj Sharma (58141), John Whittaker (225547), Juan P Casas (67158), Aroon D Hingorani (67157), Roshan Ariyaratnam (379014), Liam Smeeth (67156)   +5 more
core   +1 more source

Associations of methylene tetrahydrofolate reductase (MTHFR) polymorphism with hepatocellular carcinoma in Egyptian population

Egyptian Liver Journal
Liver serves as a hub for key metabolic pathways such as folate cycle that provides one-carbon units for a network of metabolic reactions. Methylenetetrahydrofolate reductase (MTHFR) is a rate limiting enzyme in folate metabolism and thus it is vital for
Fatma Abozeid, Maysaa Zaki, Wafaa Nagah, Amany Ragab, Aya fathy, Dina Elhammady, Hayam Ghazy, Ahmed Yassen, Mohamed Serria, Omar Ammar, Maha Ragab, Manal Nomir   +11 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Thrombotic Risk Evaluation of Two Methylenetetrahydrofolate Reductase Mutations C677t and A1298c in Venous Thromboembolism

The MTHFR mutations C677T and A1298C combined with folate and vitamin B12 deficiency lead to hypercoagulability. We evaluated thrombotic risk due to MTHFR mutations, individually and in combination, in patients with venous thromboembolism (VTE).
Irena Jukić, Bingulac- Popović, Jasna, Jasna Bingulac- Popović, Kolundžić, Monika, Jukić, Irena, Renata Kundid, Tatjana Kereš, Ana Hećimović, Svagu\u161a, Tomo, Kundid, Renata, Svaguša, Tomo, Kere\u161, Tatjana, Juki\u107, Irena, Ivana Babić, Kolund\u17ei\u107, Monika, He\u107imovi\u107, Ana, Babić, Ivana, Monika Kolundžić, Babi\u107, Ivana, Bingulac-Popovi\u107, Jasna, Tomo Svaguša, Kereš, Tatjana, Hećimović, Ana   +22 more
core   +1 more source

Forest plot of association between MTHFR C677T polymorphism and NSCL/P risk in children (T vs. C).

, 2014
Forest plot of association between MTHFR C677T polymorphism and NSCL/P risk in children (T vs. C).
Yue Zhang (30585), Baosen Zhou (102670), Mengmeng Zhao (514789), Li Shen (110858), Yangwu Ren (540810)   +4 more
core   +1 more source

Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients

, 2018
Methylenetetrahydrofolate reductase ( MTHFR) gene polymorphism (C677T)] is a well-recognized genetic risk factor for venous thrombosis; however, its association with arterial thrombosis is still under debate. Herein, we evaluated the prevalence of MTHFR
Elísio Costa, Elsa Bronze-Rocha, Sopio Garakanidze, Giorgi Nikolaishvili, Rusudan Khukhunaishvili, Irina Nakashidze, Nona Kakauridze, Marina Koridze, Sarfraz Ahmad, Alice Santos-Silva, Salome Glonti   +10 more
core   +1 more source

Meta-analyses of MTHFR C677T polymorphism and cervical cancer susceptibility after omitting the studies.

, 2013
Abbreviations and definitions: CI, 95% confidence intervals; OR, odds ratio; PQ, P value of Q test for heterogeneity; F, fixed-effect models.aMTHFR C677T polymorphism and cervical cancer susceptibility after excluding the three studies of Shekari M et al.
Shaoli Deng (149549), Ming Chen (115604), Lili Yu (149552), Kai Chang (149548), Jian Han (211805)   +4 more
core   +1 more source

急性淋巴细胞白血病患儿亚甲基四氢叶酸还原酶基因多态性与甲氨蝶呤动态血药浓度相关性的研究

Zhongguo shiyan zhenduanxue, 2010
目的本研究旨在探讨亚甲基四氢叶酸还原酶（MTHFR）C677T、A1298C基因多态性对急性淋巴细胞白血病（ALL）患儿使用大剂量甲氨蝶呤（HD-MTX）化疗期间的MTX动态血药浓度的相关关系。方法 35例ALL患儿外周血,提取基因DNA,应用PCR-RFLP方法检测MTHFR C677T、A1298C基因型;应用荧光偏振免疫分析法（FPIA）24h、48h、72h监测患儿外周血中甲氨蝶呤动态血药浓度。结果 MTHFR C677T各基因型间24 h MTX浓度有差异（P0.05）。结论 MTHFR ...
许宏, 张亚南, 康熙雄
doaj