A Preclinical Model for the ATLL Lymphoma Subtype With Insights Into the Role of Microenvironment in HTLV-1-Mediated Lymphomagenesis [PDF]
Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with Human T cell Leukemia Virus type 1 (HTLV-1) infection. Among its four main clinical subtypes, the prognosis of acute and lymphoma variants remains poor. The long latency (
Mattia Vicario +8 more
doaj +4 more sources
Functional Characterization of ycao in Escherichia coli C91 Reveals Its Role in Siderophore Production, Iron-Limited Growth, and Antimicrobial Activity [PDF]
Background: The emergence of antibiotic-resistant bacteria is one of the top health concerns. Escherichia coli is a Gram-negative bacterium that commonly causes severe infections. However, this research exposed its antibiotic-producing potential. Methods:
Khadijah M. Dashti +3 more
doaj +2 more sources
Cytotoxic Effects of a Triorganotin Derivative on HTLV-1-Infected Cells at Different Immortalization/Transformation Stages In Vitro [PDF]
Among the metal-derived complexes, recently, tin derivatives have been investigated as promising anti-cancer drug candidates. Our previous study showed that the tin-based compound Bu3SnOCOCF3 (TBT) exerts cytotoxic activity on solid tumor cell lines.
Valeria Stefanizzi +11 more
doaj +2 more sources
Establishing stable and highly osteogenic hiPSC-derived MSCs for 3D-printed bone graft through microenvironment modulation by CHIR99021-treated osteocytes [PDF]
Human induced pluripotent stem cell (hiPSC)-derived mesenchymal stem cells (iMSCs) are ideal candidates for the production of standardised and scalable bioengineered bone grafts.
Qiuling Guo +8 more
doaj +2 more sources
Food risk in consumers' eye and their consumption responses: evidence from Hanoi survey [PDF]
Purpose – This paper analyses Hanoi consumers' evaluation of food risk and response to the perceived risk. Design/methodology/approach – The authors employed the mixed method approach that integrates segmentation analysis on the survey data and ...
Thanh Mai Ha +2 more
doaj +1 more source
The discovery and application of small molecules is one of the practical strategies of safe osteogenic drugs. The small molecule CHIR99021 (C91) is a highly specific, safe, and most effective GSK-3β Inhibitor.
Bo Wang +6 more
doaj +1 more source
Single-Crystal-to-Single-Crystal Transformation in a Copper(II) Complex: Structural and Spectroscopic Insights into Methanol Elimination and Hydrogen Bond Network Formation. [PDF]
A methanol‐ligated copper(II) complex undergoes a single‐crystal‐to‐single‐crystal transformation upon solvent loss, retaining crystallinity while reorganizing its coordination geometry and hydrogen‐bonding network. This study investigates the single‐crystal‐to‐single‐crystal (SCSC) transformations of a copper(II) complex, [Cu(L1)2(acac)2]·2CH3OH (1 ...
Mirtamizdoust B +4 more
europepmc +2 more sources
Whole‐genome analysis of the ammonia‐oxidizing bacterium, Nitrosomonas eutropha C91: implications for niche adaptation [PDF]
Summary Analysis of the structure and inventory of the genome of Nitrosomonas eutropha C91 revealed distinctive features that may explain the adaptation of N. eutropha ‐like bacteria to N‐saturated ecosystems.
Stein, L.Y. +12 more
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Mortality from cancer and non-cancer diseases in the Lithuanian cohort of Chernobyl cleanup workers (2001-2020). [PDF]
What's new? Following the Chernobyl disaster, workers were recruited from formerly Soviet‐occupied areas, including Lithuania, to participate in clean‐up efforts. Radiation exposure incurred by workers during these efforts offers a unique opportunity for the study of long‐term health effects.
Steponaviciene R +3 more
europepmc +2 more sources
My2-Acetone-diacetone[my3-tris(trifluoromethyl)methanolato]bis[my2-tris(trifluoromethyl)methanolato]trilithium [PDF]
The title compound, [Li3(C4F9O)3(C3H6O)3], features an open Li/O cube with an Li ion missing at one corner. Three of the four bridging O atoms of the cube carry a fluorinated tert-butyl residue, whereas the fourth is part of an acetone molecule.
Vitze, Hannes +2 more
core +3 more sources

