Results 11 to 20 of about 2,855 (168)

A Highly Selective GSK-3β Inhibitor CHIR99021 Promotes Osteogenesis by Activating Canonical and Autophagy-Mediated Wnt Signaling

open access: yesFrontiers in Endocrinology, 2022
The discovery and application of small molecules is one of the practical strategies of safe osteogenic drugs. The small molecule CHIR99021 (C91) is a highly specific, safe, and most effective GSK-3β Inhibitor.
Bo Wang   +6 more
doaj   +1 more source

Functional and Molecular Characterization of C91S Mutation in the Second Epidermal Growth Factor-like Domain of Factor VII [PDF]

open access: yesIranian Journal of Biotechnology, 2018
Coagulation Factor VII is a vitamin K-dependent serine protease which has a pivotal role in the initiation of the coagulation cascade. The congenital Factor VII deficiency is a recessive hemorrhagic disorder that occurs due to mutations of F7 gene. In the present study C91S (p.C91S) substitution was detected in a patient with FVII deficiency.
Mashayekhi, Amir   +2 more
  +7 more sources

Measure for measure: Effects of money exposure, reward size and loss aversion on cheating

open access: yesCurrent Research in Behavioral Sciences, 2023
People sometimes behave dishonestly to collect undeserved monetary rewards. Prior research has shown that people put more effort into avoiding monetary losses than into making gains, and accordingly they cheat more to avoid losses than to acquire the ...
Loreta Cannito   +2 more
doaj   +1 more source

Applying Adam Smith's Theory of Moral Sentiments to elicited social norms: Giving and taking in dictator games

open access: yesSocial Sciences and Humanities Open, 2022
The main contribution of this paper lies in applying Adam Smith's moral theory to explain how some actions become jointly recognized as socially appropriate while others do not, and how these jointly recognized rules affect actual behavior. To illustrate
Nina Serdarevic, Sigve Tjøtta
doaj   +1 more source

A Statistical Explanation of the Dunning–Kruger Effect

open access: yesFrontiers in Psychology, 2022
An explanation of the Dunning–Kruger effect is provided which does not require any psychological explanation, because it is derived as a statistical artifact.
Jan R. Magnus, Anatoly A. Peresetsky
doaj   +1 more source

A Preclinical Model for the ATLL Lymphoma Subtype With Insights Into the Role of Microenvironment in HTLV-1-Mediated Lymphomagenesis

open access: yesFrontiers in Microbiology, 2018
Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with Human T cell Leukemia Virus type 1 (HTLV-1) infection. Among its four main clinical subtypes, the prognosis of acute and lymphoma variants remains poor. The long latency (
Mattia Vicario   +8 more
doaj   +1 more source

Microsponge-derived mini tablets loaded with immunosuppressive agents: Pharmacokinetic investigation in human volunteers, cell viability and IVIVC correlation

open access: yesSaudi Pharmaceutical Journal, 2023
Sirolimus, a potent immunosuppressant, has been demonstrated to have remarkable activity in inhibiting allograft rejection in transplantation.
Yasir Mehmood   +5 more
doaj   +1 more source

Bounded rationality in Keynesian beauty contests: a lesson for central bankers?

open access: yesEconomics: Journal Articles, 2020
The great recession (2008) triggered an apparent discrepancy between empirical findings and macroeconomic models based on rational expectations alone.
Mauersberger Felix   +2 more
doaj   +1 more source

Right evaluation of marketing stimuli with neuroscience. An electroencephalography experiment

open access: yesComputers in Human Behavior Reports, 2020
Emotional valence is very important in order to create the imprint of the memory of brands and companies in the minds of consumers and to create an adequate perception of companies and influence their purchasing decisions.
Antonio González-Morales
doaj   +1 more source

Negociación y preferencias económicas por género: evidencia experimental en México

open access: yesEl Trimestre Económico, 2018
Antecedentes: En México, las mujeres obtienen un menor salario en promedio que los hombres. Si bien la discriminación explica parte de esta brecha, en este artículo mostramos que existen otras causales que contribuyen a ella.Metodología: Implementamos un
Eva Olimpia Arceo Gómez   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy