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Mitochondrial VDAC, the Na+/Ca2+ Exchanger, and the Ca2+ Uniporter in Ca2+ Dynamics and Signaling

2017
Mitochondrial Ca2+ uptake and release play pivotal roles in cellular physiology by regulating intracellular Ca2+ signaling, energy metabolism, and cell death. Ca2+ transport across the inner and outer mitochondrial membranes (IMM, OMM, respectively), is mediated by several proteins, including the voltage-dependent anion channel 1 (VDAC1) in the OMM ...
Varda, Shoshan-Barmatz, Soumasree, De
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The Role of Local Ca2+ Release for Ca2+ Alternans and SR-Ca2+ Leak

2017
Cardiac Ca2+ is the second messenger transducing electrical signals into mechanical responses during excitation-contraction coupling (ECC). The unique morphology of ventricular myocytes plays a pivotal role during ECC and assures the synchronous Ca2+ release into the cytosol and the orchestrated interplay of the channels and modulators involved ...
Karin P. Hammer, Lars S. Maier
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Ca2+-induced Ca2+ release from fragmented sarcoplasmic reticulum: Ca2+-dependent passive Ca2+ efflux.

Journal of biochemistry, 1984
Characterization of the putative Ca2+-gated Ca2+ channel of sarcoplasmic reticulum, which is thought to mediate Ca2+-induced Ca2+ release, was carried out in order to elucidate the mechanism of Ca2+-induced Ca2+ release. Heavy and light fractions of fragmented sarcoplasmic reticulum isolated from rabbit skeletal muscle were loaded passively with Ca2 ...
Y, Kirino, M, Osakabe, H, Shimizu
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Ca2+-induced Ca2+ Release

2006
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Ca2+-Induced Ca2+ Release from Fragmented Sarcoplasmic Reticulum: Ca2+-Dependent Passive Ca2+ Efflux1