Results 271 to 280 of about 667,052 (292)
Some of the next articles are maybe not open access.
Ca2+ resting current and Ca2+-induced Ca2+ release in insect neurosecretory neurons
NeuroReport, 1998The effect of a Ca2+ resting current on spiking and intracellular Ca2+ concentration [Ca2+]i of isolated cockroach dorsal unpaired median neurons was investigated by combining microfluometry (Fura2) with patchclamping. The resting current was reduced by 10 microM 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) and 10 microM mefenamic acid, which ...
M, Heine, D, Wicher
openaire +2 more sources
Mitochondrial VDAC, the Na+/Ca2+ Exchanger, and the Ca2+ Uniporter in Ca2+ Dynamics and Signaling
2017Mitochondrial Ca2+ uptake and release play pivotal roles in cellular physiology by regulating intracellular Ca2+ signaling, energy metabolism, and cell death. Ca2+ transport across the inner and outer mitochondrial membranes (IMM, OMM, respectively), is mediated by several proteins, including the voltage-dependent anion channel 1 (VDAC1) in the OMM ...
Varda, Shoshan-Barmatz, Soumasree, De
openaire +2 more sources
Na+/Ca2+ Exchange and Cellular Ca2+ Homeostasis
Journal of Bioenergetics and Biomembranes, 1998The Na+/Ca2+ exchange system is the primary Ca2+ efflux mechanism in cardiac myocytes, and plays an important role in controlling the force of cardiac contraction. The exchanger protein contains 11 transmembrane segments plus a large hydrophilic domain between the 5th and 6th transmembrane segments; the transmembrane regions are responsible for ...
openaire +2 more sources
Ca2+-ATPase and Ca2+/Cation Antiporters
2020The Ca2+ in the cytoplasm has to be kept under very low levels and hence requires extrusion or efflux mechanism for this job. Two families of active transporters in the plant cell facilitate the transport function. The P-type ATPases (ER-Type Ca2+-ATPases (ECA) and P2B are autoinhibited Ca2+-ATPases (ACA)) and the Ca2+/cation antiporter (CaCA) members ...
Girdhar K. Pandey, Sibaji K. Sanyal
openaire +1 more source
The Role of Local Ca2+ Release for Ca2+ Alternans and SR-Ca2+ Leak
2017Cardiac Ca2+ is the second messenger transducing electrical signals into mechanical responses during excitation-contraction coupling (ECC). The unique morphology of ventricular myocytes plays a pivotal role during ECC and assures the synchronous Ca2+ release into the cytosol and the orchestrated interplay of the channels and modulators involved ...
Karin P. Hammer, Lars S. Maier
openaire +1 more source
T-type Ca2+ current contribution to Ca2+-induced Ca2+ release in developing myocardium
Journal of Molecular and Cellular Cardiology, 2003In normal adult-ventricular myocardium, Ca2+-induced Ca2+ release (CICR) from the sarcoplasmic reticulum (SR) is activated via Ca2+ entry through L-type Ca2+ channels. However, embryonic-ventricular myocytes have a prominent T-type Ca2+ current (ICa,T).
Susan A, Kitchens +2 more
openaire +2 more sources
Journal of biochemistry, 1984
Characterization of the putative Ca2+-gated Ca2+ channel of sarcoplasmic reticulum, which is thought to mediate Ca2+-induced Ca2+ release, was carried out in order to elucidate the mechanism of Ca2+-induced Ca2+ release. Heavy and light fractions of fragmented sarcoplasmic reticulum isolated from rabbit skeletal muscle were loaded passively with Ca2 ...
Y, Kirino, M, Osakabe, H, Shimizu
openaire +1 more source
Characterization of the putative Ca2+-gated Ca2+ channel of sarcoplasmic reticulum, which is thought to mediate Ca2+-induced Ca2+ release, was carried out in order to elucidate the mechanism of Ca2+-induced Ca2+ release. Heavy and light fractions of fragmented sarcoplasmic reticulum isolated from rabbit skeletal muscle were loaded passively with Ca2 ...
Y, Kirino, M, Osakabe, H, Shimizu
openaire +1 more source