Results 51 to 60 of about 4,062 (173)

Chimeric Antigen Receptor Based Therapy as a Potential Approach in Autoimmune Diseases: How Close Are We to the Treatment?

Frontiers in Immunology, 2020
Despite significant breakthroughs in understanding of immunological and physiological features of autoimmune diseases, there is currently no specific therapeutic option with prolonged remission.
Muhammad Sadeqi Nezhad, Muhammad Sadeqi Nezhad, Alexander Seifalian, Nader Bagheri, Sajad Yaghoubi, Mohammad Hossein Karimi, Meghdad Adbollahpour-Alitappeh   +6 more
doaj   +1 more source

Three Adult Cases of ADHD With Comorbid Tic Symptoms Successfully Treated With Guanfacine Monotherapy

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Guanfacine extended‐release can be an effective monotherapy for adults with ADHD and comorbid tic disorders. A low dose of guanfacine was sufficient to produce a rapid improvement in tic symptoms in each patient before improving ADHD symptoms. ABSTRACT Tic disorders typically begin in childhood and often improve by adulthood, but some individuals ...
Koji Tada, Teruo Tada, Takashi Tsuboi, Koichiro Watanabe   +3 more
wiley   +1 more source

Engineered Bi-Specific AChR CAAR T Cells for Selective Elimination of Myasthenia Gravis B Cells

Research Square
SUMMARY Myasthenia gravis (MG) is an autoimmune neuromuscular disorder caused by autoantibodies targeting the nicotinic acetylcholine receptor (nAChR), which can lead to severe disability and life-threatening crises.
Niels von Wardenburg, G. Spagni, S. Reincke, Stephanie Wernick, Hans-Christian Kornau, V. Zinnow, Amelya Keles, Lucie Y. Li, Marie A Homeyer, S. Blumenau, M. Stecklum, Dietmar Schmitz, A. Pelz, Valentina Damato, N. Sanderson, Tobias Derfuss, M. C. Pham, K. C. O’Connor, Andreas Meisel, H. Prüss   +19 more
semanticscholar   +1 more source

Hybrid‐Assisted Foam Drying of Tomato Puree: Process Kinetics, Energy Efficiency, and Quality Attributes Using Sapindus mukorossi as a Natural Foaming Agent

Journal of Food Process Engineering, Volume 49, Issue 9, September 2026.
Hybrid‐assisted foam drying of tomato puree using natural Sapindus mukorossi extract improved drying kinetics, foam stability, and powder flowability while reducing energy consumption. The process enhanced moisture diffusivity and preserved bioactive compounds and color quality, demonstrating strong potential for sustainable production of functional ...
Edanur Türk, Muhammed Taşova, Osman Nuri Öcalan, Emircan Dinçer   +3 more
wiley   +1 more source

A new therapeutic pathway in autoimmune diseases: chimeric antigen receptor T cells (CAR-T) targeting specific cell subtypes or antigen-specific B lymphocytes—a brief review [PDF]

Exploration of Immunology
In hematological malignancies, autologous immunotherapy with T lymphocytes expressing a chimeric antigen receptor (CAR-T) has been successfully applied.
María Fernanda Segovia, Diana Landoni, Yohana Defranchi, Rodrigo Calderón Jofré, Carlos A. Flores Olivares, Gerson D. Keppeke   +5 more
doaj   +1 more source

Antigen-Specific Immunomodulation: CAAR-T cells Redefine Precision Therapy in Pemphigus Vulgaris

Journal of cellular immunology
Current therapies for antibody-mediated autoimmune diseases largely rely on broad immunosuppression or lineage-wide B-cell depletion. These approaches are associated with increased risks of infection and other adverse effects.
Huijie Yuan, Lu Zhao, Xu-Ming Mao
semanticscholar   +1 more source

Investigating the Impact of Fast‐Paced Digital Content, Social Media Engagement, and Lifestyle Factors on Attention, Cognitive Load, and Behavioral Impulsivity: A Machine Learning Approach

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background The increase in fast‐paced digital content and changes in lifestyle among young adults have raised concerns about their effects on cognitive functions. While many studies have looked into this connection, few have used strong machine learning models to predict subclinical cognitive outcomes based on real‐world, self‐reported ...
Arfatul Islam Asif, Sanjoy Das Joy, Mustakim Billah, Unayes Ahmed Khan, Ibnul Mansib, Sheikh Md. Azizul Hoque Munna, Anupam Kumar Bairagi, Abdullah Al Noman   +7 more
wiley   +1 more source

Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation

Frontiers in Cell and Developmental Biology, 2021
The Hippo pathway is a conserved signaling network regulating organ development and tissue homeostasis. Dysfunction of this pathway may lead to various diseases, such as regeneration defect and cancer.
Yiju Wei, Wei Li, Wei Li
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, Volume 13, Issue 37, 3 July 2026.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Tool Wear Estimation from Acoustic Emissions: A Model Incorporating Wear Rate [PDF]

, 2001
Almost all prior work on modeling the dependence of acoustic emissions on tool wear have concentrated on the effect of wear-level on the sound. We give justification for including the wear-rate information contained in the sound to improve estimation of ...
Baras, John S., Varma, S.
core   +1 more source