Results 41 to 50 of about 31,236 (144)

Role of Cellulose Acetate Butyrate on Phase Inversion: Molecular Dynamics and DFT Studies of Moxifloxacin and Benzydamine HCl Within an In Situ Forming Gel

Polysaccharides
Solvent-exchange-induced in situ forming gel (ISG) refers to a drug delivery system that transforms from a solution state into a gel or solid matrix upon administration into the body and exposure to physiological aqueous fluid.
Kritamorn Jitrangsri, Napaphol Puyathorn, Warakon Thammasut, Poomipat Tamdee, Nuttapon Yodsin, Jitnapa Sirirak, Sai Myo Thu Rein, Thawatchai Phaechamud   +7 more
doaj   +1 more source

Early experiences with usage of long‐acting injectable cabotegravir among adults in rural Ugandan and Kenyan communities: qualitative research from the SEARCH “Dynamic Choice HIV Prevention” intervention trials

Journal of the International AIDS Society
Introduction Despite oral HIV pre‐exposure prophylaxis (PrEP) effectiveness, uptake and adherence remains a challenge. Newer HIV prevention technologies, including long‐acting injectable cabotegravir (CAB‐LA), are promising for addressing known barriers ...
Carol S. Camlin, Anjeline Onyango, Jason Johnson‐Peretz, Cecilia Akatukwasa, Titus O. Arunga, Lawrence Owino, Frederick Atwine, Ambrose Byamukama, Andrew Mutabazi, Laura B. Balzer, Maggie Czarnogorski, Elijah Kakande, Helen Sunday, Gabriel Chamie, James Ayieko, Maya Petersen, Nicole Sutter, Moses R. Kamya, Diane V. Havlir, Jane Kabami   +19 more
doaj   +1 more source

Community advisory board members’ perspectives on their contributions to a large multistate cluster RCT: a mixed methods study

Journal of Clinical and Translational Science
Background: Community advisory boards (CABs) are an established approach to ensuring research reflects community priorities. This paper examines two CABs that are part of the HEALing Communities Study which aims to reduce overdose mortality.
Julie Bosak, Mari-Lynn Drainoni, Mia-Cara Christopher, Bethany Medley, Sandra Rodriguez, Sydney Bell, Erin Kim, Caroline Stotz, Greer Hamilton, Carol Bigsby, Faizah Gillen, Jennifer Kimball, Craig McClay, Kim Powers, Galya Walt, Tracy Battaglia, Deborah Chassler, Linda Sprague Martinez, Karsten Lunze   +18 more
doaj   +1 more source

Evaluation of long‐acting cabotegravir safety and pharmacokinetics in pregnant women in eastern and southern Africa: a secondary analysis of HPTN 084

Journal of the International AIDS Society
Introduction Long‐acting injectable cabotegravir (CAB‐LA) for pre‐exposure prophylaxis significantly reduced HIV acquisition in HPTN 084. We report on the safety and CAB‐LA pharmacokinetics in pregnant women during the blinded period of HPTN 084. Methods
Sinead Delany‐Moretlwe, Brett Hanscom, Xu Guo, Clemensia Nkabiito, Patricia Mandima, Patricia Ntege Nahirya, Juliet Mpendo, Muchaneta Bhondai‐Mhuri, Nyaradzo Mgodi, Rebecca Berhanu, Jennifer Farrior, Estelle Piwowar‐Manning, Susan L. Ford, Craig W. Hendrix, Alex R. Rinehart, James F. Rooney, Adeola Adeyeye, Raphael J. Landovitz, Myron S. Cohen, Mina C. Hosseinipour, Mark A. Marzinke, the HPTN 084 Study Team   +21 more
doaj   +1 more source

Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis

Frontiers in Pharmacology
IntroductionChemotherapeutic agents, despite their toxicities, variability in individual response, and risk of drug-drug interactions, are essential in the treatment of gastrointestinal cancers.
Robert Siegel, Sophie Schlosser-Hupf, Martina Müller-Schilling, Samer A. Kharroubi, André Gessner, Nahed El-Najjar, Nahed El-Najjar   +6 more
doaj   +1 more source

Real-world data of CanAssist Breast- first immunohistochemistry and AI-based prognostic test

Scientific Reports
CanAssist Breast (CAB), an immunohistochemistry (IHC) and artificial intelligence-based prognostic test, was developed on Hormone receptor-positive (HR +), HER2/neu-negative (HER2-) breast tumors from Indian patients and validated in retrospective global
Tejal Deepak Durgekar, Manvi Sunder, Badada Ananthamurthy Savitha, Payal Shrivastava, Rahul Bhagat, Naveen Krishnamoorthy, Deepti K. Shivashimpi, Manjiri Bakre   +7 more
doaj   +1 more source

Meteorological Changes Across Curiosity Rover’s Traverse Using REMS Measurements and Comparisons Between Measurements and MRAMS Model Results

Remote Sensing
The Curiosity rover, from NASA’s Mars Science Laboratory (MSL), has climbed nearly 740 m from its landing location at −4500.971 m in Gale Crater to a location reached on sol 3967 on the slopes of Mt. Sharp at −3765.27 m.
María Ruíz, Eduardo Sebastián-Martínez, Jose Antonio Rodríguez-Manfredi, Jorge Pla-García, Manuel de la Torre-Juarez, Scot C. R. Rafkin   +5 more
doaj   +1 more source

Metagenome-Assembled Genomes (MAGs): Advances, Challenges, and Ecological Insights

Microorganisms
Metagenome-assembled genomes (MAGs) have revolutionized microbial ecology by enabling the genome-resolved study of uncultured microorganisms directly from environmental samples.
Salvador Mirete, Mercedes Sánchez-Costa, Jorge Díaz-Rullo, Carolina González de Figueras, Pablo Martínez-Rodríguez, José Eduardo González-Pastor   +5 more
doaj   +1 more source

Introducing the UK Crop Microbiome Cryobank data resource, AgMicrobiomeBase, with case studies and methods on metabarcoding analyses

Environmental Microbiome
Background Here, we describe AgMicrobiomeBase as an output of the UK Crop Microbiome Cryobank (UKCMCB) project, including details of the underlying meta-barcode sequence-based methods and three microbiome analysis case studies.
Payton To Yau, Rodrigo G. Taketani, J. Miguel Bonnin, Helen Stewart, Catriona M.A. Thompson, Ian M. Clark, Tim H. Mauchline, Jacob G. Malone, Matthew J. Ryan, Susan Jones, Nicola Holden   +10 more
doaj   +1 more source

A Cab Ride [PDF]

The American Journal of Tropical Medicine and Hygiene, 2019
openaire   +2 more sources