Results 91 to 100 of about 12,023 (229)

Modeling Accuracy and Variability of Motor Timing in Treated and Untreated Parkinson’s Disease and Healthy Controls [PDF]

, 2011
Parkinson’s disease (PD) is characterized by difficulty with the timing of movements. Data collected using the synchronization–continuation paradigm, an established motor timing paradigm, have produced varying results but with most studies finding ...
Claassen, Daniel O, Dirnberger, Georg, Jahanshahi, Marjan, Jones, Catherine RG, Kubovy, Michael, Malone, Tim, Spies, Jeffrey R, Yu, Minhong   +7 more
core   +4 more sources

Effect of pergolide treatment on insulin dysregulation in horses and ponies with pituitary pars intermedia dysfunction

Equine Veterinary Journal, Volume 57, Issue 6, Page 1612-1622, November 2025.
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli, Nicholas J. Bamford, Madison L. Erdody, Skye A. Mackenzie, Tobias Warnken, Patricia A. Harris, Martin N. Sillence, Simon R. Bailey   +7 more
wiley   +1 more source

Single Dose of a Dopamine Agonist Impairs Reinforcement Learning in Humans: Behavioral Evidence from a Laboratory-based Measure of Reward Responsiveness [PDF]

, 2010
Rationale. The dopaminergic system, particularly D2-like dopamine receptors, has been strongly implicated in reward processing. Animal studies have emphasized the role of phasic dopamine (DA) signaling in reward-related learning, but these processes ...
Culhane, Melissa, Evins, Anne, Frank, Michael J., Pajtas, Petra E., Pizzagalli, Diego A, Santesso, Diane L., Schetter, Erika Cowman   +6 more
core   +1 more source

Immune dysregulation as a key driver of peripartum cardiomyopathy – an exploratory advanced imaging and biomarker study

European Journal of Heart Failure, Volume 27, Issue 10, Page 1868-1880, October 2025.
Physiological postpartum remodelling and the pathological processes involved in peripartum cardiomyopathy (PPCM). 18FDG‐PET‐CT, 18F‐fluorodeoxyglucose positron emission tomography‐computed tomography; CCL3, chemokine (C‐C motif) ligand 3; CMR, cardiovascular magnetic resonance; CRP, C‐reactive protein; CSF‐1, colony‐stimulating factor 1; CXCL10 ...
Julian Hoevelmann, Charle Viljoen, Tessa Kotze, Carlos Libhaber, Stephen Jermy, Morné Kahts, Fareda Jakoet‐Bassier, Petronella Samuels, Olivia Briton, Lynette Cilliers, Denise Hilfiker‐Kleiner, Peter van der Meer, Michael Böhm, Ntobeko A.B. Ntusi, Karen Sliwa   +14 more
wiley   +1 more source

Managing Cushing's disease: the state of the art. [PDF]

, 2014
Cushing's disease is a rare chronic disease caused by a pituitary adenoma, which leads to excess secretion of adrenocorticotropic hormone (ACTH). The over-production of ACTH leads to hyperstimulation of the adrenal glands and a chronic excess of cortisol,
Boscaro M, Casanueva FF, COLAO, ANNAMARIA, FERONE, DIEGO   +3 more
core   +1 more source

Cancer in pregnancy: FIGO Best practice advice and narrative review

International Journal of Gynecology &Obstetrics, Volume 171, Issue 1, Page 131-151, October 2025.
Abstract Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high‐income and low‐ and middle‐income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell‐free DNA testing for aneuploidy.
Surabhi Nanda, Melanie Nana, Long Nguyen‐Hoang, Sumaiya Adam, Fionnuala McAuliffe, Lina Bergman, Sarikapan Wilailak, Orla McNally, Cynthia V. Maxwell, Nikhil Purandare, Bo Jacobsson, Virna P. Medina, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Ernesto Castelazo, Graeme N. Smith, Sharleen L. O'Reilly, Patrick O'Brien, Mark Hanson, Mary L. Rosser, Claudio Sosa, Valerie Guinto, Jonathan Berek, Catherine Nelson‐Piercy, Frédéric Amant, Liona Poon, on behalf of the FIGO Committee on the Impact of Pregnancy on Long‐term Health, FIGO Committee on Women's Cancer, and the FIGO Division of Maternal and Newborn Health   +29 more
wiley   +1 more source

A Novel Case of Spontaneous Coronary Artery Dissection During Cabergoline Therapy for Prolactinoma

JACC: Case Reports, 2020
We present a case of spontaneous coronary artery dissection associated with cabergoline treatment for prolactinoma. A 31-year-old woman with history of hypertension and prolactinoma, treated with cabergoline, presented with chest pain.
Shinichiro Ikeda, MD, Jeffrey Le, MD, Shivani Verma, MD, Benjamin A. Youdelman, MD   +3 more
doaj   +1 more source

A prospective longitudinal study of Pasireotide in Nelson's syndrome [PDF]

, 2018
PURPOSE: Nelson's syndrome is a challenging condition that can develop following bilateral adrenalectomy for Cushing's disease, with high circulating ACTH levels, pigmentation and an invasive pituitary tumor. There is no established medical therapy.
A Colao, A Colao, A Colao, A Colao, A Dornhorst, A Lacroix, A Munir, AA Kasperlik-Zaluska, AN Elias, Ashley B. Grossman, B Ambrosi, Constantine Girio-Fragkoulakis, CS Graffeo, DH Nelson, Eleni Daniel, G Assie, G Assie, G Gwinup, I Shimon, I Shraga-Slutzky, IL Wapnir, J Marek, John Newell-Price, K Hayashi, L Katznelson, L Kvols, LA Casulari, LJ Hofland, M Andreassen, M Reincke, Miguel Debono, MJ Levy, P Loli, PA Kelly, Peter J. Trainer, PJ Jenkins, R Pivonello, R Pivonello, RA Feelders, RR Henry, Scott A. Akker, Sharon Caunt, Stephen J. Walters, SW Lamberts, VJ Moyes, WJ Mauermann   +45 more
core   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

MedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan, Sana Khurshid, Saud Almawash, Rakesh Kumar, Ammira S. Al‐Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha   +6 more
wiley   +1 more source

Diosmin versus cabergoline for prevention of ovarian hyperstimulation syndrome

Middle East Fertility Society Journal, 2017
Background: OHSS (Ovarian Hyperstimulation Syndrome) is the most serious iatrogenic complication of ovulation induction. The pathophysiology of OHSS is characterised by increased capillary permeability, leading to leakage of fluid from the vascular ...
Ahmed Samy Saad, Khalid Abd Aziz Mohamed
doaj   +1 more source