Results 171 to 180 of about 346,942 (313)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Computer-aided detection thresholds can guide repeat rapid molecular testing in TB screening. [PDF]

IJTLD Open
Datta B, Story A, Rogers E, Kapoor S, Raju R, Goyal P, Prakash A, Tripathy JP, Jaiswal A, Hayward A, Guleria R, Trehan N.   +11 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Coronary Artery Disease and Preoperative Coronary Angiography in Elective Thoracic Endovascular Aortic Repair: A Retrospective Cohort Study. [PDF]

J Cardiovasc Dev Dis
Hamiko M, Keswani L, Bayram A, Rondorf T, Spaeth A, Silaschi M, Zimmer S, Probst C, Nickenig G, Ahmad AE, Bakhtiary F, Schahab N.   +11 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The Harmonization of CAD Communication Skills for Concurrent Engineering: Success Story about EU Funded Project

This article describes the experience of the implementation in Riga Technical University of the project “The Harmonization of CAD Communication Skills for Concurrent Engineering” which was supported from European Union.
Dobelis, Modris
core  

IUM-hybrid model for enhanced CAD diagnosis using deep learning and VS Grad-CAM visualization. [PDF]

Sci Rep
Revathi CK, Santhi H.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Omentin-1 Val109Asp polymorphism and increased coronary artery disease risk in smokers with type 2 diabetes. [PDF]

Medicine (Baltimore)
Yu D, Tong L, Ma X, Gu N, Lu D, Yu N, Wang Y, Zhang J, Li J, Guo X.   +9 more
europepmc   +1 more source