Results 171 to 180 of about 12,242,462 (299)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Association of Salivary HIF-1α Level With Epithelial and Mesenchymal Markers in Smokers and Nonsmokers With Periodontitis: A Case-Control Study. [PDF]

Int J Dent
Kareem BE, Saliem SS.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Comparison of surface integrity, longevity of posterior tooth-colored crowns fabricated by conventional, CAD/CAM, and 3D printing techniques. [PDF]

Front Dent Med
Hunt T, Nichols J, Harmon P, Abubakr NH.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Impact of Thermocycling and Artificial Aging on the Flexural Strength and Fracture Resistance of CAD/CAM Dental Ceramics: A Systematic Review and Meta-Analysis. [PDF]

Dent J (Basel)
Mora Bayas JM, Chauca Bajaña L, Ortiz Bustamante C, Ordoñez Balladares A, Ordoñez Balladares A, Cedeño Sánchez LV, Saltos Noboa R, Sandoval Benalcázar DC, Alvarez Centeno TG, Carrion Bustamante I, Salazar Minda C, Flor Ronquillo DA, Velasquez Ron B.   +12 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Occlusal Adjustment in Free-End Implant-Supported Restorations: Digital Scans Versus Conventional Impressions With Full- and Half-Arch Techniques. [PDF]

Clin Exp Dent Res
Nakhaei M, Dashti H, Shahri A, Rahmani M, Kazemian A, Sabzevari S, Rezaee M.   +6 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Artificial Intelligence-Assisted Pulmonary Nodule Diagnosis by Thoracic Surgeons: A Comparative Study on Clinical Effectiveness. [PDF]

Thorac Cancer
Jeon YJ, Jeong J, Park D, Kang JH, Hong EK, Chung Y, Park B, Park SY.   +7 more
europepmc   +1 more source